phosphoramide mustard

One of a number of chemically-related alkylating agents with antineoplastic properties. The prototype of this group of agents is cyclophosphamide… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1973-2017
051019732017

Papers overview

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1995
1995
Phosphoramide mustard-induced DNA interstrand cross-links were studied both in vitro and by computer simulation. The local… (More)
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1991
1991
Although cyclophosphamide (CPA) is an ovarian toxicant, the responsible metabolite(s) have not been identified. The purpose of… (More)
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1991
1991
The conjugations of cyclophosphamide and of phosphoramide mustard with glutathione are shown to be catalyzed by hepatic cytosolic… (More)
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1990
1990
By a sensitive and quantitative fluorometric assay, brain and plasma time-dependent concentration profiles were generated for… (More)
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1986
1986
A Yoshida sarcoma cell line (YR/cyclo) showing decreased sensitivity to metabolically activated cyclophosphamide in vitro has… (More)
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1983
1983
Male rats were given cyclophosphamide (50 mg/kg, i.p.), and the plasma concentrations of 4-hydroxycyclophosphamide and… (More)
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1982
1982
The rates at which 4-hydroperoxycyclophosphamide and 4-hydroxycyclophosphamide are converted to phosphoramide mustard and… (More)
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1980
1980
Phosphoramide mustard, an active metabolite of cyclophosphamide, has been reacted separately with guanosine and deoxyguanosine in… (More)
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1976
1976
The relative alkylating activities of two of the cytotoxic metabolites of cyclophosphamide, phosphoramide mustard and nornitrogen… (More)
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1975
1975
Thin-layer chromatography and mass spectrometry were used to isolate and identify cyclophosphamide metabolites present in blood… (More)
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