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phosphoramide mustard

One of a number of chemically-related alkylating agents with antineoplastic properties. The prototype of this group of agents is cyclophosphamide… Expand
National Institutes of Health

Papers overview

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2011
2011
Healthy oocytes are critical for producing healthy children, but little is known about whether or not oocytes have the capacity… Expand
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Highly Cited
2008
Highly Cited
2008
PURPOSE Bendamustine has shown clinical activity in patients with disease refractory to conventional alkylator chemotherapy. The… Expand
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Highly Cited
2003
Highly Cited
2003
Liver toxicity caused by high-dose myeloablative therapy leads to significant morbidity after hematopoietic cell transplantation… Expand
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Highly Cited
1991
Highly Cited
1991
Although cyclophosphamide (CPA) is an ovarian toxicant, the responsible metabolite(s) have not been identified. The purpose of… Expand
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1984
1984
Plasma half-life and area under the curve (AUC) values for cyclophosphamide were determined in patients given this agent iv at… Expand
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Highly Cited
1982
Highly Cited
1982
Abstract Cyclophosphamide must be metabolically activated to have maximal mutagenic or teratogenic activity. The first step in… Expand
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Highly Cited
1979
Highly Cited
1979
Haemorrhagic cystitis of the bladder caused by the antitumour agents cyclophosphamide {2-[bis(2-chloroethyl)amino]tetrahydro-2H-1… Expand
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Review
1979
Review
1979
SummaryCyclosphosphamide is widely used for cancer chemotherapy and for immunosuppression. The parent compound is inactive in… Expand
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1978
1978
Unambiguous and sensitive methods based on gas chromatography-chemical ionization mass spectrometry have been developed to… Expand
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Highly Cited
1976
Highly Cited
1976
The relative alkylating activities of two of the cytotoxic metabolites of cyclophosphamide, phosphoramide mustard and nornitrogen… Expand
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