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phosphoramide mustard

One of a number of chemically-related alkylating agents with antineoplastic properties. The prototype of this group of agents is cyclophosphamide… 
National Institutes of Health

Related topics

Related topics

2 relations
NCIt Antineoplastic Agent Terminology

Broader (1)

Phosphoramide Mustards

Papers overview

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Highly Cited
2022
Highly Cited
2022
Effect of unconventional feeds on production cost, growth performance and expression of quantitative genes in growing pigs
This study examined the effects of unconventional feed on performance characteristics and candi-date gene expression in growing… 
Review
2004
Review
2004
NITROREDUCTASE: A PRODRUG‐ACTIVATING ENZYME FOR CANCER GENE THERAPY
1. The prodrug CB1954 (5‐(aziridin‐1‐yl)‐2,4‐dinitrobenzamide) is activated by Escherichia coli nitroreductase (NTR) to a potent… 
Review
1999
Review
1999
The enzymes of glutathione synthesis: gamma-glutamylcysteine synthetase.
The metabolite glutathione fulfills many important and chemically complex roles in protecting cellular components from the… 
Highly Cited
1998
Highly Cited
1998
Pharmacokinetics of cyclophosphamide and its metabolites in bone marrow transplantation patients
Review
1984
Review
1984
Cyclophosphamide (Cytoxan). A review on relevant pharmacology and clinical uses.
Highly Cited
1980
Highly Cited
1980
Alkylation of guanosine and deoxyguanosine by phosphoramide mustard.
Phosphoramide mustard, an active metabolite of cyclophosphamide, has been reacted separately with guanosine and deoxyguanosine in… 
Highly Cited
1978
Highly Cited
1978
Quantitation by gas chromatography-chemical ionization mass spectrometry of cyclophosphamide, phosphoramide mustard, and nornitrogen mustard in the plasma and urine of patients receiving…
Unambiguous and sensitive methods based on gas chromatography-chemical ionization mass spectrometry have been developed to… 
Highly Cited
1976
Highly Cited
1976
Alkylating properties of phosphoramide mustard.
The relative alkylating activities of two of the cytotoxic metabolites of cyclophosphamide, phosphoramide mustard and nornitrogen… 
Highly Cited
1975
Highly Cited
1975
Isolation and mass spectral identification of blood metabolites of cyclophosphamide: evidence for phosphoramide mustard as the biologically active metabolite.
Thin-layer chromatography and mass spectrometry were used to isolate and identify cyclophosphamide metabolites present in blood… 
Highly Cited
1974
Highly Cited
1974
Some studies of the active intermediates formed in the microsomal metabolism of cyclophosphamide and isophosphamide.
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