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Phosphoramide Mustards

Known as: Mustards, Phosphoramide, Phosphoramide Mustards [Chemical/Ingredient] 
A group of nitrogen mustard compounds which are substituted with a phosphoramide group or its derivatives. They are usually cytotoxic and used as… 
National Institutes of Health

Related topics

Related topics

19 relations

Narrower (12)

2,3-didechloroethylifosfamideGVF protocolN,N-diethylphosphoramideTH 302

Broader (1)

Antineoplastic Agents, Alkylating
In Bloodagonistsantagonists & inhibitorsaspects of radiation effects

Papers overview

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2015
2015
Chemo- and Enantioselective Addition and β-Hydrogen Transfer Reduction of Carbonyl Compounds with Diethylzinc Reagent in One Pot Catalyzed by a Single Chiral Organometallic Catalyst.
Using a single chiral phosphoramide-Zn(II) complex as the catalyst, the asymmetric β-H transfer reduction of aromatic… 
2004
2004
The problem of specificity and selectivity of alkylating cytostatics; studies on N-2-chloroethylamido-oxazaphosphorines
a) N-2-chloroethylamido-oxazaphosphorines such as cyclophosphamide, ifosfamide and trofosfamide differ from “non-oxazaphosphorine… 
1998
1998
Nitrobenzyl-Based Photosensitive Phosphoramide Mustards: Synthesis and Photochemical Properties of Potential Prodrugs for Cancer Therapy.
Several nitrobenzyl-based photosensitive phosphoramide mustards were synthesized. The nitrobenzyl moiety was structurally varied… 
1993
1993
Protonation of phosphoramide mustard and other phosphoramides.
The chemistry of the bifunctional alkylating agent phosphoramide mustard and model phosphoramides was probed by multinuclear NMR… 
Highly Cited
1992
Highly Cited
1992
Hypoxia-selective antitumor agents. 5. Synthesis of water-soluble nitroaniline mustards with selective cytotoxicity for hypoxic mammalian cells.
Nitroaniline mustards have potential as hypoxia-selective cytotoxic agents, with reductive metabolism activating the nitrogen… 
1987
1987
The cytonucleus test in the rat: a combined metaphase and micronucleus assay.
1976
1976
Synthesis of steroidal cyclophosphamides
1976
1976
Cyclophosphamide (NSC-26271)-related phosphoramide mustards- recent advances and historical perspective.
The antitumor activity of three of the most phosphoramide mustards, NSC-69947, NSC-72505, and NSC-72510, was compared with that… 
1971
1971
The action of mono- and di-functional sulphur mustards on the ribonucleic acid-containing bacteriophage mu2.
Bacteriophage mu2 is inactivated by both mono- and di-functional sulphur mustards at relatively low extents of alkylation. No… 
1966
1966
Potential carcinolytic agents. IV. Diazoamino mustards.
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