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phosphatidylinositol 3,4-diphosphate

Known as: phosphatidylinositol 3,4-bisphosphate, 3,4-PIP2, PtdIns(3,4)P2 
National Institutes of Health

Related topics

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2 relations

Broader (1)

Phosphatidylinositol Phosphates
phosphoinositide-3,4-bisphosphate

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2006
Review
2006
Regulation of phosphoinositide signaling by the inositol polyphosphate 5‐phosphatases
Phosphoinositide signaling molecules control cellular growth, proliferation and differentiation, intracellular vesicle… 
Review
2005
Review
2005
The SH2 domain containing inositol polyphosphate 5-phosphatase-2: SHIP2.
2005
2005
Long Chain CoA Esters as Competitive Antagonists of Phosphatidylinositol 4,5-Bisphosphate Activation in Kir Channels*
Long chain fatty acid esters of coenzyme A (LC-CoA) are potent activators of ATP-sensitive (KATP) channels, and elevated levels… 
Highly Cited
1998
Highly Cited
1998
A Novel Integrin-activated Pathway Forms PKB/Akt- stimulatory Phosphatidylinositol 3,4-Bisphosphate via Phosphatidylinositol 3-Phosphate in Platelets*
The aggregation of human platelets is an important physiological hemostatic event contingent upon receptor-dependent activation… 
Highly Cited
1997
Highly Cited
1997
A target of phosphatidylinositol 3,4,5-trisphosphate with a zinc finger motif similar to that of the ADP-ribosylation-factor GTPase-activating protein and two pleckstrin homology domains.
We have purified a protein that binds phosphatidylinositol 3,4,5-trisphosphate [PtdIns(3,4,5)P3] using beads bearing a PtdIns(3,4… 
1997
1997
Selective Recognition of Phosphatidylinositol 3,4,5-Trisphosphate by a Synthetic Peptide*
The present study takes a novel approach to explore the mode of action of phosphoinositide 3-kinase lipid products by identifying… 
Highly Cited
1993
Highly Cited
1993
Tyrosine kinases and phosphoinositide metabolism in thrombin-stimulated human platelets.
In this study we have examined the implication of tyrosine kinase activities in aggregation, 5-hydroxytryptamine secretion and… 
Highly Cited
1991
Highly Cited
1991
Involvement of platelet glycoprotein IIb-IIIa (alpha IIb-beta 3 integrin) in thrombin-induced synthesis of phosphatidylinositol 3',4'-bisphosphate.
Highly Cited
1990
Highly Cited
1990
Human platelets form 3-phosphorylated phosphoinositides in response to alpha-thrombin, U46619, or GTP gamma S.
Highly Cited
1990
Highly Cited
1990
Epidermal growth factor increases the labeling of phosphatidylinositol 3,4-bisphosphate in MA-10 Leydig tumor cells.
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