phosphatidylinositol 3,4-diphosphate

Known as: phosphatidylinositol 3,4-bisphosphate, 3,4-PIP2, PtdIns(3,4)P2 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1985-2017
05101519852017

Papers overview

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Highly Cited
2005
Highly Cited
2005
Generation and turnover of phosphoinositides (PIs) must be coordinated in a spatial- and temporal-restricted manner. The small… (More)
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Highly Cited
2002
Highly Cited
2002
An important class of phosphorylated phosphoinositides carrying a phosphate group at the 3' position of the inositol ring are… (More)
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Highly Cited
2002
Highly Cited
2002
The products of PI 3-kinase activation, PtdIns(3,4,5)P3 and its immediate breakdown product PtdIns(3,4)P2, trigger physiological… (More)
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Highly Cited
2000
Highly Cited
2000
3-Methyladenine which stops macroautophagy at the sequestration step in mammalian cells also inhibits the phosphoinositide 3… (More)
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Highly Cited
2000
Highly Cited
2000
The PTEN gene is a tumor suppressor localized in the frequently altered chromosomal region 10q23. The tumor suppressor function… (More)
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Highly Cited
1999
Highly Cited
1999
Phosphoinositide 3-kinases (PI3Ks) are ubiquitous lipid kinases that function both as signal transducers downstream of cell… (More)
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Highly Cited
1998
Highly Cited
1998
Protein kinase B (PKB) is activated in response to phosphoinositide 3-kinases and their lipid products phosphatidylinositol 3,4… (More)
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Highly Cited
1997
Highly Cited
1997
BACKGROUND Protein kinase B (PKB), also known as c-Akt, is activated rapidly when mammalian cells are stimulated with insulin and… (More)
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Highly Cited
1997
Highly Cited
1997
BACKGROUND The activation of protein kinase B (PKB, also known as c-Akt) is stimulated by insulin or growth factors and results… (More)
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Highly Cited
1997
Highly Cited
1997
The avian sarcoma virus 16 (ASV 16) is a retrovirus that induces hemangiosarcomas in chickens. Analysis of the ASV 16 genome… (More)
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