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phosphatidylinositol 3,4-diphosphate

Known as: phosphatidylinositol 3,4-bisphosphate, 3,4-PIP2, PtdIns(3,4)P2 
 
National Institutes of Health

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Highly Cited
2007
Highly Cited
2007
Phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2) and phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) are lipid… Expand
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Highly Cited
2005
Highly Cited
2005
Generation and turnover of phosphoinositides (PIs) must be coordinated in a spatial- and temporal-restricted manner. The small… Expand
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Highly Cited
2003
Highly Cited
2003
Fish is a scaffolding protein and Src substrate. It contains an amino-terminal Phox homology (PX) domain and five Src homology 3… Expand
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Highly Cited
2002
Highly Cited
2002
p47(phox) is a key cytosolic subunit required for activation of phagocyte NADPH oxidase. The X-ray structure of the p47(phox) PX… Expand
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Highly Cited
2000
Highly Cited
2000
The PTEN gene is a tumor suppressor localized in the frequently altered chromosomal region 10q23. The tumor suppressor function… Expand
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Highly Cited
2000
Highly Cited
2000
Pleckstrin homology (PH) domains are protein modules of around 120 amino acids found in many proteins involved in cellular… Expand
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Highly Cited
1998
Highly Cited
1998
Phosphatidylinositol 3-kinase (PI3K) mediates a variety of cellular responses by generating PtdIns(3,4)P2 and PtdIns(3,4,5)P3… Expand
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Highly Cited
1997
Highly Cited
1997
BACKGROUND Protein kinase B (PKB), also known as c-Akt, is activated rapidly when mammalian cells are stimulated with insulin and… Expand
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Highly Cited
1997
Highly Cited
1997
BACKGROUND The activation of protein kinase B (PKB, also known as c-Akt) is stimulated by insulin or growth factors and results… Expand
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Highly Cited
1997
Highly Cited
1997
The avian sarcoma virus 16 (ASV 16) is a retrovirus that induces hemangiosarcomas in chickens. Analysis of the ASV 16 genome… Expand
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