Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

phosphatidylinositol 3,4-diphosphate

Known as: phosphatidylinositol 3,4-bisphosphate, 3,4-PIP2, PtdIns(3,4)P2 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Phosphatidylinositol Phosphates
phosphoinositide-3,4-bisphosphate

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
The Adaptor Protein Fish Associates with Members of the ADAMs Family and Localizes to Podosomes of Src-transformed Cells*
Fish is a scaffolding protein and Src substrate. It contains an amino-terminal Phox homology (PX) domain and five Src homology 3… Expand
Highly Cited
2002
Highly Cited
2002
Binding of the PX domain of p47phox to phosphatidylinositol 3,4‐bisphosphate and phosphatidic acid is masked by an intramolecular interaction
p47phox is a key cytosolic subunit required for activation of phagocyte NADPH oxidase. The X‐ray structure of the p47phox PX… Expand
Highly Cited
2001
Highly Cited
2001
The PX domains of p47phox and p40phox bind to lipid products of PI(3)K
PX domains are found in a variety of proteins that associate with cell membranes, but their molecular function has remained… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Highly Cited
2000
Highly Cited
2000
Phosphorylation of the PTEN Tail Regulates Protein Stability and Function
ABSTRACT The PTEN gene is a tumor suppressor localized in the frequently altered chromosomal region 10q23. The tumor suppressor… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Highly Cited
1997
Highly Cited
1997
Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Bα
BACKGROUND Protein kinase B (PKB), also known as c-Akt, is activated rapidly when mammalian cells are stimulated with insulin and… Expand
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
Highly Cited
1997
Highly Cited
1997
3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase
BACKGROUND The activation of protein kinase B (PKB, also known as c-Akt) is stimulated by insulin or growth factors and results… Expand
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Highly Cited
1997
Highly Cited
1997
Transformation of chicken cells by the gene encoding the catalytic subunit of PI 3-kinase.
The avian sarcoma virus 16 (ASV 16) is a retrovirus that induces hemangiosarcomas in chickens. Analysis of the ASV 16 genome… Expand
Highly Cited
1997
Highly Cited
1997
High Affinity Binding of Inositol Phosphates and Phosphoinositides to the Pleckstrin Homology Domain of RAC/Protein Kinase B and Their Influence on Kinase Activity*
The influence of inositol phosphates and phosphoinositides on the α isoform of the RAC-protein kinase B (RAC/PKB) was studied… Expand
  • figure 1
  • table I
  • figure 3
  • figure 5
  • figure 4
Highly Cited
1996
Highly Cited
1996
p150Ship, a signal transduction molecule with inositol polyphosphate-5-phosphatase activity.
The production, survival, and function of monocytes and macrophages is regulated by the macrophage colony-stimulating factor (M… Expand
Review
1994
Review
1994
Phosphatidylinositol 3‐kinase
  • Rosana Kapeller, L. Cantley
  • BioEssays : news and reviews in molecular…
  • 1994
    • Corpus ID: 39196874
Currently, a central question in biology is how signals from the cell surface modulate intracellular processes. In recent years… Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE