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phosphatidylinositol 3,4-diphosphate

Known as: phosphatidylinositol 3,4-bisphosphate, 3,4-PIP2, PtdIns(3,4)P2 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Phosphatidylinositol Phosphates
phosphoinositide-3,4-bisphosphate

Papers overview

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Highly Cited
2002
Highly Cited
2002
Binding of the PX domain of p47phox to phosphatidylinositol 3,4‐bisphosphate and phosphatidic acid is masked by an intramolecular interaction
p47phox is a key cytosolic subunit required for activation of phagocyte NADPH oxidase. The X‐ray structure of the p47phox PX… 
Highly Cited
2001
Highly Cited
2001
The PX domains of p47phox and p40phox bind to lipid products of PI(3)K
PX domains are found in a variety of proteins that associate with cell membranes, but their molecular function has remained… 
Highly Cited
2000
Highly Cited
2000
Phosphorylation of the PTEN Tail Regulates Protein Stability and Function
ABSTRACT The PTEN gene is a tumor suppressor localized in the frequently altered chromosomal region 10q23. The tumor suppressor… 
Highly Cited
1998
Highly Cited
1998
Identification and analysis of PH domain‐containing targets of phosphatidylinositol 3‐kinase using a novel in vivo assay in yeast
Phosphatidylinositol 3‐kinase (PI3K) mediates a variety of cellular responses by generating PtdIns(3,4)P2 and PtdIns(3,4,5)P3… 
Highly Cited
1997
Highly Cited
1997
Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Bα
Highly Cited
1997
Highly Cited
1997
3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase
Highly Cited
1997
Highly Cited
1997
Transformation of chicken cells by the gene encoding the catalytic subunit of PI 3-kinase.
The avian sarcoma virus 16 (ASV 16) is a retrovirus that induces hemangiosarcomas in chickens. Analysis of the ASV 16 genome… 
Highly Cited
1996
Highly Cited
1996
p150Ship, a signal transduction molecule with inositol polyphosphate-5-phosphatase activity.
The production, survival, and function of monocytes and macrophages is regulated by the macrophage colony-stimulating factor (M… 
Review
1994
Review
1994
Phosphatidylinositol 3‐kinase
Currently, a central question in biology is how signals from the cell surface modulate intracellular processes. In recent years… 
Highly Cited
1985
Highly Cited
1985
Metabolism of inositol 1,4,5-trisphosphate and inositol 1,3,4-trisphosphate in rat parotid glands.
A complete separation of myo-inositol 1,4,5-[4,5-(32)P]trisphosphate prepared from human erythrocytes, and myo-[2-3H]inositol 1,3… 
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