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phosphoinositide-3,4-bisphosphate

Known as: PI(3,4)P2 
National Institutes of Health

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Broader (1)

Phosphatidylinositols
phosphatidylinositol 3,4-diphosphate

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Phosphatidylinositol-3,4-Bisphosphate and Its Binding Protein Lamellipodin Regulate Chemotaxis of Malignant B Lymphocytes
Cell migration is controlled by PI3Ks, which generate lipid messengers phosphatidylinositol-3,4,5-trisphosphate and… 
2016
2016
Depletion of Inositol Polyphosphate 4-Phosphatase II Suppresses Callosal Axon Formation in the Developing Mice
The corpus callosum is a bundle of nerve fibers that connects the two cerebral hemispheres and is essential for coordinated… 
2015
2015
Endosome and INPP4B
Phosphoinositide 3-kinase (PI3K) and AKT define a signaling network that regulates important biological processes such as cell… 
2013
2013
The carboxyl tail of alpha-actinin-4 regulates its susceptibility to m-calpain and thus functions in cell migration and spreading.
2007
2007
Regulation of PDGF‐stimulated SHIP2 tyrosine phosphorylation and association with Shc in 3T3‐L1 preadipocytes
In 3T3‐L1 and human preadipocytes, insulin results in the isolated rise in phosphatidylinositol (PI)‐3,4,5‐P3, whereas PDGF… 
Review
2005
Review
2005
Phosphoinositide lipid second messengers: new paradigms for transepithelial signal transduction
Multiple forms of phosphatidylinositol are generated by differential phosphorylation of the inositol headgroup. These… 
2005
2005
A modelling framework describing the enzyme regulation of membrane lipids underlying gradient perception in Dictyostelium cells II: input-output analysis.
2003
2003
Loss of a single allele of SHIP exacerbates the immunopathology of Pten heterozygous mice
Phosphatidylinositol 3-kinase (PI3K) has emerged as a critical component of multiple immune system intracellular signalling… 
Highly Cited
1998
Highly Cited
1998
Disruption of Dictyostelium PI3K genes reduces [32P]phosphatidylinositol 3,4 bisphosphate and [32P]phosphatidylinositol trisphosphate levels, alters F-actin distribution and impairs pinocytosis.
To understand how phosphatidylinositol 3-kinase (PI3K) modulates cell structure and function, we examined the molecular and… 
1996
1996
The 3-phosphorylated phosphoinositide response of 3T3-L1 preadipose cells exposed to insulin, insulin-like growth factor-1, or platelet-derived growth factor.
We compared the pattern of 3-phosphorylated phosphoinositides produced by confluent 3T3-L1 preadipose cells upon exposure to… 
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