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phosphoinositide-3,4-bisphosphate

Known as: PI(3,4)P2 
National Institutes of Health

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2 relations

Broader (1)

Phosphatidylinositols
phosphatidylinositol 3,4-diphosphate

Papers overview

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Highly Cited
2013
Highly Cited
2013
Spatiotemporal control of endocytosis by phosphatidylinositol-3,4-bisphosphate
Phosphoinositides serve crucial roles in cell physiology, ranging from cell signalling to membrane traffic. Among the seven… 
Highly Cited
2013
Highly Cited
2013
Tks5 and SHIP2 Regulate Invadopodium Maturation, but Not Initiation, in Breast Carcinoma Cells
Highly Cited
2008
Highly Cited
2008
SopB promotes phosphatidylinositol 3-phosphate formation on Salmonella vacuoles by recruiting Rab5 and Vps34
Salmonella colonizes a vacuolar niche in host cells during infection. Maturation of the Salmonella-containing vacuole (SCV… 
Highly Cited
2003
Highly Cited
2003
Allosteric Activation of PTEN Phosphatase by Phosphatidylinositol 4,5-Bisphosphate*
Phosphatase and tensin homologue deleted on chromosome 10 (PTEN) is a tumor suppressor that is lost in many human tumors and… 
Highly Cited
2001
Highly Cited
2001
Overexpression of SH2-Containing Inositol Phosphatase 2 Results in Negative Regulation of Insulin-Induced Metabolic Actions in 3T3-L1 Adipocytes via Its 5′-Phosphatase Catalytic Activity
ABSTRACT Phosphatidylinositol (PI) 3-kinase plays an important role in various metabolic actions of insulin including glucose… 
Highly Cited
1999
Highly Cited
1999
A novel SH2-containing phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase (SHIP2) is constitutively tyrosine phosphorylated and associated with src homologous and collagen gene (SHC) in chronic…
Because of the probable causal relationship between constitutive p210(bcr/abl) protein tyrosine kinase activity and… 
Highly Cited
1998
Highly Cited
1998
MSS4, a Phosphatidylinositol-4-phosphate 5-Kinase Required for Organization of the Actin Cytoskeleton in Saccharomyces cerevisiae *
The Saccharomyces cerevisiae protein MSS4 is essential and homologous to mammalian phosphatidylinositol-4-phosphate (PI(4)P) 5… 
Highly Cited
1998
Highly Cited
1998
Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC
Highly Cited
1998
Highly Cited
1998
Insulin-dependent translocation of ARNO to the plasma membrane of adipocytes requires phosphatidylinositol 3-kinase
Highly Cited
1989
Highly Cited
1989
Transient increase in phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol trisphosphate during activation of human neutrophils.
We recently showed that phosphatidylinositol trisphosphate (PIP3) was present in a unique lipid fraction generated in neutrophils… 
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