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phosphatidic acid biosynthetic process

Known as: phosphatidic acid formation, phosphatidic acid biosynthesis, phosphatidic acid synthesis 
The chemical reactions and pathways resulting in the formation of phosphatidic acid, any derivative of glycerol phosphate in which both the remaining… 
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
YLR099C (ICT1) Encodes a Soluble Acyl-CoA-dependent Lysophosphatidic Acid Acyltransferase Responsible for Enhanced Phospholipid Synthesis on Organic Solvent Stress in Saccharomyces cerevisiae*
One of the major determinants of organic solvent tolerance is the increase in membrane phospholipids. Here we report for the… 
Highly Cited
2004
Highly Cited
2004
Ral and Phospholipase D2-Dependent Pathway for Constitutive Metabotropic Glutamate Receptor Endocytosis
G-protein-coupled receptors play a central role in the regulation of neuronal cell communication. Class 1 metabotropic glutamate… 
Highly Cited
2003
Highly Cited
2003
ADP-ribosylation Factor-dependent Phospholipase D2 Activation Is Required for Agonist-induced μ-Opioid Receptor Endocytosis*
Agonist exposure of many G protein-coupled receptors induces a rapid receptor phosphorylation and uncoupling from G proteins… 
Highly Cited
1999
Highly Cited
1999
Redundant Systems of Phosphatidic Acid Biosynthesis via Acylation of Glycerol-3-Phosphate or Dihydroxyacetone Phosphate in the Yeast Saccharomyces cerevisiae
ABSTRACT In the yeast Saccharomyces cerevisiae lipid particles harbor two acyltransferases, Gat1p and Slc1p, which catalyze… 
Highly Cited
1997
Highly Cited
1997
Fatty acid binding protein: stimulation of microsomal phosphatidic acid formation.
The effect of fatty acid binding proteins (FABPs) on two key steps of microsomal phosphatidic acid formation was examined. Rat… 
Highly Cited
1989
Highly Cited
1989
Compartmentation of hepatic fatty-acid-binding protein in liver cells and its effect on microsomal phosphatidic acid biosynthesis.
Fatty-acid-binding proteins are known to occur in the cytosol of mammalian cells and to bind fatty acids and their CoA-esters… 
Highly Cited
1988
Highly Cited
1988
Biochemical profile of risperidone, a new antipsychotic.
Risperidone was compared to the 5-hydroxytryptamine2 antagonist ritanserin and to the dopamine-D2 antagonist haloperidol. The in… 
Highly Cited
1987
Highly Cited
1987
Inositol 1,4,5-triphosphate-induced granule secretion in platelets. Evidence that the activation of phospholipase C mediated by platelet thromboxane receptors involves a guanine nucleotide binding…
Phosphoinositide hydrolysis in platelets stimulated by thrombin is thought to be regulated by a pertussis toxin-sensitive guanine… 
Highly Cited
1972
Highly Cited
1972
Positional distribution and turnover of fatty acids in phosphatidic acid, phosphinositides, phosphatidylcholine and phosphatidylethanolamine in rat brain in vivo.
Highly Cited
1963
Highly Cited
1963
Diglyceride kinase and other path ways for phosphatidic acid synthesis in the erythrocyte membrane.
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