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phorone

Known as: 2,6-dimethyl-2,5- heptadien-4-one, diisopropylideneacetone 
 
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
BACKGROUND/AIMS To evaluate the role of mitochondrial oxidative stress and permeability transition (MPT) in isoniazid (INH) and… Expand
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Highly Cited
2003
Highly Cited
2003
Transcription factor NF-E2-related factor 2 (Nrf2) regulates the induction of antioxidative proteins, including heme oxygenase-1… Expand
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Highly Cited
2003
Highly Cited
2003
Mitochondrial oxidant stress and peroxynitrite formation have been implicated in the pathophysiology of acetaminophen-induced… Expand
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1998
1998
Phorone, a glutathione (GSH) depletor, induces the expression of mRNAs of heme oxygenase-1 (HO-1) and c-jun by mediating the… Expand
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1996
1996
This study shows that induction of heme oxygenase-1 (HO-1) gene expression by a glutathione (GSH) depletor, phorone, is inhibited… Expand
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Highly Cited
1995
Highly Cited
1995
Ferritin, by regulating the "free" intracellular iron pool, controls iron-catalyzed generation of reactive oxygen species, but… Expand
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Highly Cited
1992
Highly Cited
1992
These studies examine the in vivo formation of a unique series of PGF2-like compounds (F2-isoprostanes) derived from free radical… Expand
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Highly Cited
1991
Highly Cited
1991
Metallothionein (MT) is a low-molecular-weight protein with a high cysteine content that has been proposed to play a role in… Expand
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Review
1981
Review
1981
Publisher Summary The method for lowering tissue glutathione (GSH) levels involves the administration of compounds that react… Expand
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1978
1978
Administration of phorone (diisopropylidene acetone), an industrial solvent, to mice caused a rapid depletion of hepatic… Expand
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