phorone

Known as: 2,6-dimethyl-2,5- heptadien-4-one, diisopropylideneacetone 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1978-2014
051019782014

Papers overview

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2007
2007
To identify candidate biomarker gene sets to evaluate the potential risk of chemical-induced glutathione depletion in livers, we… (More)
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2003
Highly Cited
2003
Transcription factor NF-E2-related factor 2 (Nrf2) regulates the induction of antioxidative proteins, including heme oxygenase-1… (More)
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2002
Highly Cited
2002
The effect of reduced glutathione (GSH) depletion by acetaminophen (APAP), diethylmaleate (DEM), or phorone on the mode of cell… (More)
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1998
1998
Phorone, a glutathione (GSH) depletor, induces the expression of mRNAs of heme oxygenase-1 (HO-1) and c-jun by mediating the… (More)
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1997
1997
The levels of lipid peroxidation product (malondialdehyde = MDA) and vitamin C and the activities of glutathione peroxidase (GSH… (More)
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1996
1996
This study shows that induction of heme oxygenase-1 (HO-1) gene expression by a glutathione (GSH) depletor, phorone, is inhibited… (More)
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1995
Highly Cited
1995
Ferritin, by regulating the "free" intracellular iron pool, controls iron-catalyzed generation of reactive oxygen species, but… (More)
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1992
Highly Cited
1992
These studies examine the in vivo formation of a unique series of PGF2-like compounds (F2-isoprostanes) derived from free radical… (More)
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1991
Highly Cited
1991
Metallothionein (MT) is a low-molecular-weight protein with a high cysteine content that has been proposed to play a role in… (More)
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1986
1986
Phorone (diisopropylidene acetone) led to a strong depletion of cellular glutathione in liver, kidney and heart but not in lung… (More)
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