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Ketones

Known as: Ketone, Ketones [Chemical/Ingredient] 
A type of chemical substance used in perfumes, paints, solvents, and found in essential oils (scented liquid taken from plants). Ketones are also… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1936-2017
0500100019362016

Related topics

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50 relations

Narrower (43)

(R,Z)-5-muscenone1-octen-3-one14-methyl-2-octadecanone2,5-heptanedione
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Ketone MeasurementKetone bodies measurement, quantitativeKetones:PrThr:24H:Urine:OrdKetones:SCnc:Pt:XXX:Qn
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Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Ketones
Ketone Measurement
congener
ketene
Butyrophenones
polyetheretherketone

Papers overview

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Highly Cited
2011
Highly Cited
2011
Ketones and lactate increase cancer cell "stemness," driving recurrence, metastasis and poor clinical outcome in breast cancer: achieving personalized medicine via Metabolo-Genomics.
Previously, we showed that high-energy metabolites (lactate and ketones) "fuel" tumor growth and experimental metastasis in an in… (More)
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Highly Cited
2011
Highly Cited
2011
Short-chain fatty acids and ketones directly regulate sympathetic nervous system via G protein-coupled receptor 41 (GPR41).
The maintenance of energy homeostasis is essential for life, and its dysregulation leads to a variety of metabolic disorders… (More)
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Highly Cited
2010
Highly Cited
2010
Ketones and lactate "fuel" tumor growth and metastasis: Evidence that epithelial cancer cells use oxidative mitochondrial metabolism.
Previously, we proposed a new model for understanding the "Warburg effect" in tumor metabolism. In this scheme, cancer-associated… (More)
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Highly Cited
2010
Highly Cited
2010
Biocatalytic asymmetric synthesis of chiral amines from ketones applied to sitagliptin manufacture.
Pharmaceutical synthesis can benefit greatly from the selectivity gains associated with enzymatic catalysis. Here, we report an… (More)
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Highly Cited
2007
Highly Cited
2007
Ketones inhibit mitochondrial production of reactive oxygen species production following glutamate excitotoxicity by increasing NADH oxidation.
Dietary protocols that increase serum levels of ketones, such as calorie restriction and the ketogenic diet, offer robust… (More)
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Highly Cited
2007
Highly Cited
2007
Hepatic fibroblast growth factor 21 is regulated by PPARalpha and is a key mediator of hepatic lipid metabolism in ketotic states.
Mice fed a high-fat, low-carbohydrate ketogenic diet (KD) exhibit marked changes in hepatic metabolism and energy homeostasis… (More)
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Highly Cited
2007
Highly Cited
2007
The cytochrome P450 enzyme CYP96A15 is the midchain alkane hydroxylase responsible for formation of secondary alcohols and ketones in stem cuticular wax of Arabidopsis.
Most aerial surfaces of plants are covered by cuticular wax that is synthesized in epidermal cells. The wax mixture on the… (More)
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Highly Cited
1993
Highly Cited
1993
Specific proteolytic cleavage of poly(ADP-ribose) polymerase: an early marker of chemotherapy-induced apoptosis.
Apoptosis is a morphologically and biochemically distinct form of cell death that occurs under a variety of physiological and… (More)
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Highly Cited
1986
Highly Cited
1986
Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor
Endothelium-derived vascular relaxing factor (EDRF)1 is a humoral agent that is released by vascular endothelium and mediates… (More)
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Highly Cited
1971
Highly Cited
1971
Ketone-body utilization by adult and suckling rat brain in vivo.
1. Ketone-body utilization in fed and starved adult and suckling rats has been investigated by measuring arterio-venous… (More)
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