Ketone Measurement

Pharmaceutical synthesis can benefit greatly from the selectivity gains associated with enzymatic catalysis. Here, we report an… (More)

Mice fed a high-fat, low-carbohydrate ketogenic diet (KD) exhibit marked changes in hepatic metabolism and energy homeostasis… (More)

Ten phenols were selected as natural laccase mediators after screening 44 different compounds with a recalcitrant dye (Reactive… (More)

BACKGROUND Within the toxicology community, considerable effort is directed toward the development of alternative methods for… (More)

During early pregnancy there is an increase in body fat accumulation, associated with both hyperphagia and increased lipogenesis… (More)

Hyperleptinemia causes disappearance of body fat without a rise in free fatty acids (FFA) or ketones, suggesting that leptin can… (More)

The parametrization and testing of the OPLS all-atom force field for organic molecules and peptides are described. Parameters for… (More)

A TOTAL deficiency in or resistance to the protein leptin causes severe obesity1–4. As leptin levels rise with increasing… (More)

We investigated the response of leptin to short-term fasting and refeeding in humans. A mild decline in subcutaneous adipocyte ob… (More)

Porcine pancreatic islets were microencapsulated in alginate-polylysine-alginate capsules and transplanted intraperitoneally into… (More)