phagophore
National Institutes of Health
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ABSTRACT To resolve the signaling mechanisms that mediate the starvation-induced processes of Dictyostelium sporulation and…
The intracellular trafficking pathway, macroautophagy, acts as a recycling and disposal service that can be upregulated during…
During autophagy, cargo molecules destined for degradation are sequestrated into a double-membrane structure called autophagosome…
Mitophagy is a degradative process that adapts the quantity and quality of mitochondria to the cellular needs. Mitochondria…
A peptide that enhances autophagy suppresses viral infections and clears protein aggregates.
We recently showed that phagophore biogenesis requires SNAREs. Our data indicate that the exocytic Q/t-SNAREs Sso1/2 and Sec9 are…
For some people, the appearance of autophagosomes by electron microscopy is the “gold standard” for demonstrating macroautophagy…
Autophagy is the major process by which cells degrade their own cytoplasm. Autophagy begins with the sequestration of a portion…