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phTX 12

Known as: PHTX-12, phTX12, philanthotoxin 12 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

PolyaminesTyrosine
analogs & derivatives

Papers overview

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2016
2016
Block of nicotinic acetylcholine receptors by philanthotoxins is strongly dependent on their subunit composition
Philanthotoxin-433 (PhTX-433) is an active component of the venom from the Egyptian digger wasp, Philanthus triangulum. PhTX-433… 
2003
2003
A sequential high-yielding large-scale solution-method for synthesis of philanthotoxin analogues.
2002
2002
Solid-phase synthesis and pharmacological evaluation of analogues of PhTX-12-A potent and selective nicotinic acetylcholine receptor antagonist.
2000
2000
Solid phase synthesis and biological evaluation of enantiomerically pure wasp toxin analogues PhTX-343 and PhTX-12.
PhTX-343 and PhTX-12, analogues of the natural polyamine wasp toxin PhTX-433, were synthesised in 40-60% yields as pure… 
2000
2000
Solid-phase synthesis and biological evaluation of a combinatorial library of philanthotoxin analogues.
The modular structure of philanthotoxins was exploited for construction of the first combinatorial library of these compounds… 
1992
1992
Synthesis of novel and photolabile philanthotoxin analogs: Glutamate receptor antagonists
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