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perflubron

Known as: perfluoroctylbromide, perflubron [Chemical/Ingredient], PFOB 
A synthetic radiopaque liquid form of perfluorooctyl bromide. Used as a contrast agent for magnetic resonance imaging (MRI), perflubron is also used… 
National Institutes of Health

Related topics

Related topics

13 relations

Narrower (7)

AF0144ImagentImagent BPImavist

Broader (4)

Anti-Obesity AgentsContrast MediaFluorocarbonsRadiation-Sensitizing Agents
cyclophosphamide/perflubronperfluorooctyl iodide

Papers overview

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Highly Cited
2011
Highly Cited
2011
Use of perfluorocarbon nanoparticles for non-invasive multimodal cell tracking of human pancreatic islets.
In vivo imaging of engraftment and immunorejection of transplanted islets is critical for further clinical development, with (1)H… 
Highly Cited
2007
Highly Cited
2007
Molecular imaging with targeted perfluorocarbon nanoparticles: quantification of the concentration dependence of contrast enhancement for binding to sparse cellular epitopes.
2004
2004
The effect of chemical stability and purification of perfluorocarbon liquids in experimental extended-term vitreous substitution
Abstract• Background: To determine the importance of chemical stability and purification of perfluorocarbon liquids (PFCLs) in… 
Highly Cited
2004
Highly Cited
2004
Cosurfactant effect of a semifluorinated alkane at a fluorocarbon/water interface: impact on the stabilization of fluorocarbon-in-water emulsions.
Previous work has demonstrated that semifluorinated alkanes CnF2n+1CmH2m+1 (FnHm diblocks), when used in conjunction with… 
Highly Cited
2002
Highly Cited
2002
Improvements in the ultrasonic contrast of targeted perfluorocarbon nanoparticles using an acoustic transmission line model
Targeted acoustic contrast agents offer the potential for sensitive ultrasonic detection of pathologic tissues. We have… 
Highly Cited
1999
Highly Cited
1999
Perfluorocarbon emulsions as intravenous delivery media for hyperpolarized xenon
The use of perfluorooctyl bromide (PFOB) emulsions as delivery media for hyperpolarized xenon has been investigated. Emulsion… 
Highly Cited
1998
Highly Cited
1998
Hemodilution and intravenous perflubron emulsion as an alternative to blood transfusion: effects on tissue oxygenation during profound hemodilution in anesthetized dogs
BACKGROUND: Intravenously administered perfluorocarbon (PFC) emulsions increase oxygen solubility in plasma. PFC might therefore… 
Highly Cited
1997
Highly Cited
1997
Perflubron decreases inflammatory cytokine production by human alveolar macrophages.
OBJECTIVE To determine whether inflammatory cytokine production by stimulated human alveolar macrophages is affected by… 
Highly Cited
1996
Highly Cited
1996
A Pilot Study of the Effects of a Perflubron Emulsion, AF 0104, on Mixed Venous Oxygen Tension in Anesthetized Surgical Patients
A pilot study of a perfluorochemical (PFC) emulsion was undertaken to determine whether administration of a perflubron emulsion… 
Review
1993
Review
1993
Perfluorocarbon-based red blood cell substitutes.
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