pegvisomant

Known as: Growth hormone, Somatotropin (18-Aspartic Acid, 21-Asparagine, 120-Lysine, 167-Asparagine, 168-Alanine, 171-Serine, 172-Arginine, 174-Serine, 179-Threonine) (Human), Pegylated, Somatotropin precursor 
A pegylated, recombinant, human growth hormone (GH) structural analog with GH receptor antagonist activity. As a GH analog, the structure of… (More)

Topic mentions per year

Topic mentions per year

1951-2018
0204019512017

Papers overview

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2009
2009
OBJECTIVE For patients with acromegaly who are suboptimally controlled on long-acting octreotide (LAR), treatment options are to… (More)
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2008
2008
CONTEXT Pegvisomant, a GH receptor antagonist, suppresses serum IGF-I levels into the normal range in more than 95% of patients… (More)
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2007
2007
OBJECTIVE The GH receptor antagonist pegvisomant is a highly effective new treatment option in acromegaly. The German Pegvisomant… (More)
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2007
2007
CONTEXT/OBJECTIVE To effectively normalize IGF-I in patients with acromegaly, various covariates may affect dosing and plasma… (More)
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Highly Cited
2006
Highly Cited
2006
CONTEXT GH deficiency is common in childhood cancer survivors. In a previous report, although we did not find an increase in the… (More)
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2005
2005
CONTEXT In clinical practice, patients with acromegaly may be switched from therapy with long-acting somatostatin analogs to… (More)
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Highly Cited
2005
Highly Cited
2005
Pegvisomant monotherapy once daily returns concentrations of insulin-like growth factor I (IGF-I) to normal in most patients with… (More)
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2001
2001
OBJECT The authors have previously demonstrated that modulation of the growth hormone (GH)/insulin-like growth factor-I (IGF-I… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Patients with acromegaly are currently treated with surgery, radiation therapy, and drugs to reduce hypersecretion of… (More)
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1995
1995
Seventy-six prepubertal children receiving autologous or allogeneic bone marrow transplantation (BMT) were enrolled in a… (More)
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