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pathologic cytolysis

Known as: Cytolysis, Cytolytic Process, lysis 
In biology, lysis refers to the breakdown of a cell caused by damage to its plasma (outer) membrane. It can be caused by chemical or physical means… 
National Institutes of Health

Related topics

Related topics

20 relations

Narrower (6)

ApoptosisAutolysisBacteriolysisHemolysis (biological function)
Cell DeathCessation of lifeIchthyosis, Cyclic, with Epidermolytic HyperkeratosisImmune System Processes

Broader (2)

Lysiscytotoxicity

Papers overview

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Highly Cited
1989
Highly Cited
1989
Induction of target cell DNA release by the cytotoxic T lymphocyte granule protease granzyme A
The rapid breakdown of target cell DNA during CTL-mediated lysis has been difficult to explain by the granule exocytosis model of… 
Highly Cited
1987
Highly Cited
1987
Cytotoxic T lymphocytes and glucocorticoids activate an endogenous suicide process in target cells
Cytotoxic T lymphocytes (CTL) induce a cytolytic process in target cells which, like the glucocorticoid-mediated cytolysis of… 
Highly Cited
1986
Highly Cited
1986
Serine esterase in cytolytic T lymphocytes
The mechanisms that enable cytotoxic T lymphocytes (Tc cells) to destroy target cells are only vaguely understood. However… 
Highly Cited
1980
Highly Cited
1980
Alloreactive cloned T cell lines. I. Interactions between cloned amplifier and cytolytic T cell lines
Several T cell clones have been derived by limiting dilution of secondary mixed leukocyte culture cells stimulated by H-2- and M… 
Review
1979
Review
1979
Do Natural Killer Cells Engage in Regulated Reactions Against Self to Ensure Homeostasis?
Host reactivities not requiring immunization in the mouse, especially natural resistance of irradiated animals to accept grafts… 
Review
1978
Review
1978
Natural killer cells in the mouse: an alternative immune surveillance mechanism?
During thelast 10 years thenumber of effector cell types active in growth inhibition or cytolysis of tumor cells has steadily… 
Highly Cited
1975
Highly Cited
1975
Cytotoxic effects of antigen- and mitogen-induced T cells on various targets.
Mitogen-induced cytotoxicity was studied by culturing mouse spleen cells with an optimum mitogenic dose of concanavalin A (Con A… 
Highly Cited
1975
Highly Cited
1975
The influence of sodium on calcium fluxes in pinched‐off nerve terminals in vitro.
1. The influence of internal and external Na concentrations on Ca movements have been measured in pinch‐off presynaptic nerve… 
Highly Cited
1974
Highly Cited
1974
Cell‐mediated cell lysis in vitro: genetic control of killer cell production and target specificities in the mouse
The requirements for killer cell production in the course of a mixed leukocyte reaction and the specificity of target cell (PHA… 
Highly Cited
1968
Highly Cited
1968
FURTHER CHARACTERIZATION OF PARTICULATE FRACTIONS FROM LYSED CELL ENVELOPES OF HALOBACTERIUM HALOBIUM AND ISOLATION OF GAS VACUOLE MEMBRANES
Lysates of cell envelopes from Halobacterium halobium have been separated into four fractions. A soluble, colorless fraction (I… 
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