parthenolide
National Institutes of Health
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MDM2 belongs to a class of ring-finger domain–containing ubiquitin ligases that mediate the proteasomal degradation of numerous…
In this study, we have examined the molecular events induced by parthenolide, a sesquiterpene lactone, and explored possible…
Purpose: Nuclear factor-κB (NF-κB), activated in multiple myeloma (MM) cells by microenvironmental cues, confers resistance to…
Heat shock proteins are generally regarded as intracellular proteins acting as molecular chaperones; however, Hsp72 is also…
Fenretinide (N-4-hydroxyphenyl retinamide, 4HPR) is a synthetic anticancer retinoid that is a well-known apoptosis-inducing agent…
Apoptosis and necrosis (“accidental cell death”) are distinct modes of cell death. The feature that often distinguishes apoptotic…
The ethanol extract of Michelia champaca and the petroleum ether extract of Talauma ovata showed activity toward the human…