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panitumumab

Known as: panitumumab [Chemical/Ingredient], ABX-EGF, Clone E7.6.3, panitumumab antibody, human 
A human monoclonal antibody that is being used to treat colorectal cancer that has spread to other parts of the body. It is used in patients whose… 
National Institutes of Health

Related topics

Related topics

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10 ML panitumumab 20 MG/ML Injection [Vectibix]HER1 Antagonists [MoA]Monoclonal AntibodiesNCIt Antineoplastic Agent Terminology

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Vectibix

Papers overview

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Review
2003
Review
2003
The epidermal growth factor receptor pathway and its inhibition as anticancer therapy.
Epidermal growth factor receptor (EGFR) is commonly overexpressed in a number of epithelial malignancies and is often associated… 
Highly Cited
2002
Highly Cited
2002
Increased plasma HB-EGF associated with obesity and coronary artery disease.
The mechanism by which the obese subjects are more associated with vascular disease remains unclear. We reported that the adipose… 
Highly Cited
1999
Highly Cited
1999
Contact-dependent Growth Inhibition and Apoptosis of Epidermal Growth Factor (EGF) Receptor-expressing Cells by the Membrane-anchored Form of Heparin-binding EGF-like Growth Factor*
Heparin-binding epidermal growth factor-like growth factor (HB-EGF) transduces mitogenic signals through the EGF receptor (EGFR… 
Highly Cited
1998
Highly Cited
1998
Extracellular calcium influx stimulates metalloproteinase cleavage and secretion of heparin‐binding EGF‐like growth factor independently of protein kinase C
The phorbol ester, tetradecanoyl‐phorbol 13‐acetate (TPA), stimulates rapid proteolytic processing of the transmembrane, pro… 
Highly Cited
1998
Highly Cited
1998
Retinoid regulation of heparin‐binding EGF‐like growth factor gene expression in human keratinocytes and skin *
Abstract: Retinoic acid (RA) has profound effects on epidermal homeostasis; however, the molecular mechanisms by which retinoids… 
Highly Cited
1994
Highly Cited
1994
Differential regulation of heparin-binding epidermal growth factor-like growth factor in the adult ovariectomized mouse uterus by progesterone and estrogen.
Expression of heparin-binding epidermal growth factor-like growth factor (HB-EGF) was studied in the adult ovariectomized mouse… 
Highly Cited
1992
Highly Cited
1992
Induction of heparin-binding epidermal growth factor-like growth factor mRNA by phorbol ester and angiotensin II in rat aortic smooth muscle cells.
Highly Cited
1992
Highly Cited
1992
Interaction of heparin-binding EGF-like growth factor (HB-EGF) with the epidermal growth factor receptor: modulation by heparin, heparinase, or synthetic heparin-binding HB-EGF fragments.
The binding of heparin-binding EGF-like growth factor (HB-EGF) to the epidermal growth factor (EGF) receptor of human endometrial… 
Highly Cited
1986
Highly Cited
1986
Oral administration of synthetic human urogastrone promotes healing of chronic duodenal ulcers in rats.
Highly Cited
1984
Highly Cited
1984
Tumor-promoting phorbol diesters mediate phosphorylation of the epidermal growth factor receptor.
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