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panipenem

Known as: 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 6-(1-hydroxyethyl)-3-((1-(1-iminoethyl)-3-pyrrolidinyl)thio)-7-oxo-, (5R-(3(S*),5alpha,6alpha(R*)))-, 6-(1-hydroxyethyl)-2-(1--acetimidoylpyrrolidin-3-ylthio)-1-carbapen-2-em-3-carboxylic acid 
A broad-spectrum parenteral carbapenem with activity against aerobic, anaerobic, gram-positive and gram-negative organisms including non-fermenters… Expand
National Institutes of Health

Papers overview

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Review
2011
Review
2011
ABSTRACT In this review, we summarize the current “state of the art” of carbapenem antibiotics and their role in our… Expand
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Highly Cited
2004
Highly Cited
2004
ABSTRACT Immature renal function in neonates requires antibiotic dosage adjustment. Population pharmacokinetic studies were… Expand
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Highly Cited
2002
Highly Cited
2002
ABSTRACT Combinations of carbapenems and epigallocatechin gallate (EGCg; a main constituent of tea catechins) showed potent… Expand
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Review
2002
Review
2002
Carbapenems are β-lactam antibiotics characterised by the presence of a β-lactam ring with a carbon instead of sulfone in the 4… Expand
Highly Cited
2001
Highly Cited
2001
ABSTRACT In 1996, Serratia marcescens KU3838 was isolated from the urine of a patient with a urinary tract infection at a… Expand
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Review
2000
Review
2000
During the last few decades, several carbapenems have been developed. The major characteristic of the newer drugs, such as MK-826… Expand
Highly Cited
1999
Highly Cited
1999
Previously, a significant decrease in the trough plasma-concentration of valproic acid (VPA) owing to the concomitant… Expand
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1998
1998
ABSTRACT There is evidence indicating that the carbapenem antibiotic panipenem decreases plasma concentrations of valproic acid… Expand
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1998
1998
Serum concentrations of valproic acid (VPA) were reduced to 0% to 40% of the original levels by concomitant use with panipenem… Expand
1993
1993
Evidence of permeation of panipenem through the OprD (D2) channel of Pseudomonas aeruginosa outer membrane was shown by using… Expand
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