panipenem

Known as: 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 6-(1-hydroxyethyl)-3-((1-(1-iminoethyl)-3-pyrrolidinyl)thio)-7-oxo-, (5R-(3(S*),5alpha,6alpha(R*)))-, 6-(1-hydroxyethyl)-2-(1--acetimidoylpyrrolidin-3-ylthio)-1-carbapen-2-em-3-carboxylic acid 
A broad-spectrum parenteral carbapenem with activity against aerobic, anaerobic, gram-positive and gram-negative organisms including non-fermenters… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1992-2016
0102019922016

Papers overview

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2006
2006
beta-Lactam antibiotics have been suggested to have some degree of convulsive activity and neurotoxicity in experimental animals… (More)
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2004
2004
Immature renal function in neonates requires antibiotic dosage adjustment. Population pharmacokinetic studies were performed to… (More)
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2002
2002
Combinations of carbapenems and epigallocatechin gallate (EGCg; a main constituent of tea catechins) showed potent synergy… (More)
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2001
2001
The population pharmacokinetics of panipenem was studied in 23 neonates. Their postconceptional age (PCA) was 24.7-42.6 weeks and… (More)
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2001
2001
In 1996, Serratia marcescens KU3838 was isolated from the urine of a patient with a urinary tract infection at a hospital in… (More)
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1999
1999
Previously, a significant decrease in the trough plasma-concentration of valproic acid (VPA) owing to the concomitant… (More)
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1998
1998
Serum concentrations of valproic acid (VPA) were reduced to 0% to 40% of the original levels by concomitant use with panipenem… (More)
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1998
1998
There is evidence indicating that the carbapenem antibiotic panipenem decreases plasma concentrations of valproic acid (VPA) in… (More)
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1993
1993
Evidence of permeation of panipenem through the OprD (D2) channel of Pseudomonas aeruginosa outer membrane was shown by using… (More)
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1992
1992
Studies were carried out on the clinical efficacy of panipenem/betamipron (PAPM/BP) against bacterial infections. The results are… (More)
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