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panipenem

Known as: 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 6-(1-hydroxyethyl)-3-((1-(1-iminoethyl)-3-pyrrolidinyl)thio)-7-oxo-, (5R-(3(S*),5alpha,6alpha(R*)))-, 6-(1-hydroxyethyl)-2-(1--acetimidoylpyrrolidin-3-ylthio)-1-carbapen-2-em-3-carboxylic acid 
A broad-spectrum parenteral carbapenem with activity against aerobic, anaerobic, gram-positive and gram-negative organisms including non-fermenters… Expand
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
BACKGROUND As the number of elderly people has increased in Japan, the occurrence of aspiration pneumonia has also increased… Expand
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Highly Cited
2004
Highly Cited
2004
ABSTRACT Immature renal function in neonates requires antibiotic dosage adjustment. Population pharmacokinetic studies were… Expand
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2003
2003
Panipenem, a parenteral carbapenem antibacterimental animals, panipenem/betamipron is recomal agent, was the second carbapenem to… Expand
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Highly Cited
2002
Highly Cited
2002
ABSTRACT Combinations of carbapenems and epigallocatechin gallate (EGCg; a main constituent of tea catechins) showed potent… Expand
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Review
2002
Review
2002
Carbapenems are β-lactam antibiotics characterised by the presence of a β-lactam ring with a carbon instead of sulfone in the 4… Expand
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Highly Cited
2001
Highly Cited
2001
ABSTRACT In 1996, Serratia marcescens KU3838 was isolated from the urine of a patient with a urinary tract infection at a… Expand
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1999
1999
Previously, a significant decrease in the trough plasma-concentration of valproic acid (VPA) owing to the concomitant… Expand
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1998
1998
ABSTRACT There is evidence indicating that the carbapenem antibiotic panipenem decreases plasma concentrations of valproic acid… Expand
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1998
1998
Serum concentrations of valproic acid (VPA) were reduced to 0% to 40% of the original levels by concomitant use with panipenem… Expand
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Review
1997
Review
1997
The nephrotoxic beta-lactam antibiotics cause acute proximal tubular necrosis. Significant renal toxicity, which has been rare… Expand
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