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panadiplon

Known as: 3-(5-cyclopropyl-1,2,4-oxadiazol 3-yl)-5-(1-methylethyl)imidazo(1,5-a)quinoxalin-4(5H)-one 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

OxadiazolesQuinoxalines

Narrower (1)

U 78875

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Overtaking the DILI Model-T
  • Alisa Opar
  • Nature Reviews Drug Discovery
  • 2012
  • Corpus ID: 37258153
A new €32 million project aimed at understanding drug-induced liver injury is the latest of several collaborative efforts that… 
Review
2009
Review
2009
Metabolomics in drug intolerance.
Adverse drug reactions appear during the clinical use of a drug and constitute a health problem, as they are an important cause… 
2005
2005
Contribution of alpha 1GABAA and alpha 5GABAA receptor subtypes to the discriminative stimulus effects of ethanol in squirrel monkeys.
Ethanol's ability to enhance GABA neurotransmission via GABA(A) receptors has been implicated as an important mechanism… 
Highly Cited
2004
Highly Cited
2004
An Integrated Model for Determining Causes of Poor Oral Drug Absorption
AbstractPurpose. To develop an integrated absorption model for estimating the fraction of dose absorbed and determining the… 
2002
2002
5-Ethoxymethyl-7-fluoro-3-oxo-1,2,3,5-tetrahydrobenzo[4,5]imidazo[1,2a]pyridine-4-N- (2-fluorophenyl)carboxamide (RWJ-51204), a New Nonbenzodiazepine Anxiolytic
5-Ethoxymethyl-7-fluoro-3-oxo-1,2,3,5-tetrahydrobenzo[4,5] imidazo[1,2a]pyridine-4-N-(2-fluorophenyl)carboxamide) (RWJ-51204… 
Review
2001
Review
2001
Metabolic, idiosyncratic toxicity of drugs: overview of the hepatic toxicity induced by the anxiolytic, panadiplon.
1999
1999
Drug discrimination analysis of partial agonists at the benzodiazepine site. I. Differential effects of U-78875 across training conditions in baboons and rats.
The benzodiazepine receptor ligand U-78875 [3-(5-cyclopro pyl-1,2, 4-oxadiazol-3-yl)-5-(1-methylethyl)imidazol(1, 5-a)quinoxalin… 
1998
1998
Disruption of mitochondrial activities in rabbit and human hepatocytes by a quinoxalinone anxiolytic and its carboxylic acid metabolite.
1995
1995
Induction of a hepatic toxic syndrome in the Dutch-belted rabbit by a quinoxalinone anxiolytic.
1994
1994
Anxiolytic Potential of Benzodiazepine Receptor Partial Agonists
SummaryAnxiety disorders are common psychiatric problems and the cause of considerable morbidity. Following the demise of the… 
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