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panadiplon
Known as:
3-(5-cyclopropyl-1,2,4-oxadiazol 3-yl)-5-(1-methylethyl)imidazo(1,5-a)quinoxalin-4(5H)-one
National Institutes of Health
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Related topics
Related topics
3 relations
Broader (2)
Oxadiazoles
Quinoxalines
Narrower (1)
U 78875
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Overtaking the DILI Model-T
Alisa Opar
Nature Reviews Drug Discovery
2012
Corpus ID: 37258153
A new €32 million project aimed at understanding drug-induced liver injury is the latest of several collaborative efforts that…
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Review
2009
Review
2009
Metabolomics in drug intolerance.
I. Andreu
,
C. Mayorga
,
M. Miranda
Current drug metabolism
2009
Corpus ID: 22397714
Adverse drug reactions appear during the clinical use of a drug and constitute a health problem, as they are an important cause…
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2005
2005
Contribution of alpha 1GABAA and alpha 5GABAA receptor subtypes to the discriminative stimulus effects of ethanol in squirrel monkeys.
D. M. Platt
,
A. Duggan
,
+4 authors
J. K. Rowlett
The Journal of pharmacology and experimental…
2005
Corpus ID: 35636903
Ethanol's ability to enhance GABA neurotransmission via GABA(A) receptors has been implicated as an important mechanism…
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Highly Cited
2004
Highly Cited
2004
An Integrated Model for Determining Causes of Poor Oral Drug Absorption
Lawrence X. Yu
Pharmaceutical Research
2004
Corpus ID: 5910972
AbstractPurpose. To develop an integrated absorption model for estimating the fraction of dose absorbed and determining the…
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2002
2002
5-Ethoxymethyl-7-fluoro-3-oxo-1,2,3,5-tetrahydrobenzo[4,5]imidazo[1,2a]pyridine-4-N- (2-fluorophenyl)carboxamide (RWJ-51204), a New Nonbenzodiazepine Anxiolytic
B. Dubinsky
,
A. H. Vaidya
,
+9 authors
R. Shank
Journal of Pharmacology and Experimental…
2002
Corpus ID: 23880756
5-Ethoxymethyl-7-fluoro-3-oxo-1,2,3,5-tetrahydrobenzo[4,5] imidazo[1,2a]pyridine-4-N-(2-fluorophenyl)carboxamide) (RWJ-51204…
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Review
2001
Review
2001
Metabolic, idiosyncratic toxicity of drugs: overview of the hepatic toxicity induced by the anxiolytic, panadiplon.
R. Ulrich
,
J. Bacon
,
E. Brass
,
C. T. Cramer
,
D. Petrella
,
E. L. Sun
Chemico-biological interactions
2001
Corpus ID: 19538543
1999
1999
Drug discrimination analysis of partial agonists at the benzodiazepine site. I. Differential effects of U-78875 across training conditions in baboons and rats.
N. Ator
,
R. Griffiths
The Journal of pharmacology and experimental…
1999
Corpus ID: 14314505
The benzodiazepine receptor ligand U-78875 [3-(5-cyclopro pyl-1,2, 4-oxadiazol-3-yl)-5-(1-methylethyl)imidazol(1, 5-a)quinoxalin…
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1998
1998
Disruption of mitochondrial activities in rabbit and human hepatocytes by a quinoxalinone anxiolytic and its carboxylic acid metabolite.
R. Ulrich
,
J. Bacon
,
+4 authors
E. Holmuhamedov
Toxicology
1998
Corpus ID: 11784314
1995
1995
Induction of a hepatic toxic syndrome in the Dutch-belted rabbit by a quinoxalinone anxiolytic.
R. Ulrich
,
J. Bacon
,
+5 authors
E. L. Sun
Toxicology
1995
Corpus ID: 4921145
1994
1994
Anxiolytic Potential of Benzodiazepine Receptor Partial Agonists
J. Potokar
,
D. Nutt
1994
Corpus ID: 71162271
SummaryAnxiety disorders are common psychiatric problems and the cause of considerable morbidity. Following the demise of the…
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