Oxadiazoles

Known as: Oxadiazoles [Chemical/Ingredient], oxadiazole 
 
National Institutes of Health

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10074-G53-hydroxymethyl-4-phenylfuroxan3-phenylsydnone4-hydroxynethyl-furoxan-3-carboxamide
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In Bloodagonistsantagonists & inhibitorschemical synthesis

Papers overview

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2012
2012
Oxadiazoles in medicinal chemistry.
Oxadiazoles are five-membered heteroaromatic rings containing two carbons, two nitrogens, and one oxygen atom, and they exist in… (More)
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2010
2010
Molecular properties prediction, synthesis and antimicrobial activity of some newer oxadiazole derivatives.
In present investigation a series of 28 oxadiazole analogues (AB1-AB28) were subjected to molecular properties prediction, drug… (More)
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Highly Cited
2009
Highly Cited
2009
Mechanism of PTC124 activity in cell-based luciferase assays of nonsense codon suppression.
High-throughput screening (HTS) assays used in drug discovery frequently use reporter enzymes such as firefly luciferase (FLuc… (More)
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2009
2009
Synthesis, antimicrobial and cytotoxic activities of 1,3,4-oxadiazoles, 1,3,4-thiadiazoles and 1,2,4-triazoles.
A new class of 1,3,4-oxadiazoles were prepared from acid hydrazides on treatment with different carboxylic acids in the presence… (More)
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2009
2009
Synthesis of novel 1,3,4-oxadiazole derivatives and their biological properties.
A novel series of 2-[3-(4-bromophenyl)propan-3-one]-5-(substituted phenyl)-1,3,4-oxadiazoles (4a-n) have been synthesized from 3… (More)
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Highly Cited
2008
Highly Cited
2008
Identification of oxadiazoles as new drug leads for the control of schistosomiasis
Treatment for schistosomiasis, which is responsible for more than 280,000 deaths annually, depends almost exclusively on… (More)
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Highly Cited
2008
Highly Cited
2008
Synthesis of new 4-pyrrol-1-yl benzoic acid hydrazide analogs and some derived oxadiazole, triazole and pyrrole ring systems: a novel class of potential antibacterial and antitubercular agents.
In the present study, a novel series of 4-pyrrol-1-yl benzoic acid hydrazide analogs, some derived 5-substituted-2-thiol-1,3,4… (More)
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2008
2008
Design, synthesis and evaluation of antiinflammatory, analgesic and ulcerogenicity studies of novel S-substituted phenacyl-1,3,4-oxadiazole-2-thiol and Schiff bases of diclofenac acid as…
Diclofenac sodium is being used for its anti-inflammatory actions since 28 years, but as all the NSAIDs are suffering from the… (More)
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2007
2007
Synthesis, antimicrobial, and anti-inflammatory activities of novel 2-(1-adamantyl)-5-substituted-1,3,4-oxadiazoles and 2-(1-adamantylamino)-5-substituted-1,3,4-thiadiazoles.
Reaction of 1-adamantanecarbonyl chloride with certain carboxylic acid hydrazides in pyridine yielded the corresponding N-acyl… (More)
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1996
1996
Design, synthesis and antiinflammatory activity of some 1,3,4-oxadiazole derivatives.
A series of substituted 1,3,4-oxadiazole derivatives 19-34 were synthesized as antiinflammatory agents. The target compounds were… (More)
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