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Medicinal prospects of antioxidants: A review.
TLDR
This review figures the various researches on pharmacological activity of natural along with synthetic antioxidant molecules. Expand
Ciprofloxacin: review on developments in synthetic, analytical, and medicinal aspects
TLDR
The available clinical evidence suggests the potentially enhanced efficacy of this drug in the treatment of various community acquired and nosocomial infections and sexually transmitted diseases, as reflected in the greater volume of distribution. Expand
Synthesis of new benzimidazole and phenylhydrazinecarbothiomide hybrids and their anticonvulsant activity
A series of new benzimidazole derivatives (4a–p) were synthesized and evaluated for anticonvulsant activity in albino mice against two most adopted models, i.e. maximal electroshock seizure (MES)-Expand
Molecular properties prediction, synthesis and antimicrobial activity of some newer oxadiazole derivatives.
TLDR
It was observed that compounds showed moderate to good antibacterial activity, but their antifungal activity was somewhat moderate, while compounds AB13 and AB20 showed pronounced activity against all bacterial and fungal strains. Expand
Synthesis and anticonvulsant activity of substituted oxadiazole and thiadiazole derivatives.
A series of five membered heterocyclics was synthesized by the reaction between isoniazid and various substituted isothiocyanates and was tested for their anticonvulsant activity by determining theirExpand
In vitro Anti-tubercular Screening of Newly Synthesized Benzimidazole Derivatives
A series of 1-(1H-benzimidazol-2-yl)-3-(substituted phenyl)-2-propen-1-one were allowed to react with hydrazine hydrate and phenyl hydrazine in submitted reactions to get pyrazoline and phenylExpand
Thiazolidine-2,4-diones derivatives as PPAR-γ agonists: synthesis, molecular docking, in vitro and in vivo antidiabetic activity with hepatotoxicity risk evaluation and effect on PPAR-γ gene
A library of conjugates of chromones and 2,4-thiazolidinedione has been synthesized by Knoevenagel condensation followed by reduction using hydrogen gas and Pd/C as a catalyst. Compounds 5c and 5eExpand
Anti-tubulin agents of natural origin: Targeting taxol, vinca, and colchicine binding domains.
TLDR
By placing all the naturally occurring taxol, vinca and colchicine binding site analogues at one place makes a better understanding of the tubulin interactions with known natural tubulin binders that would helps in the discovery of new and potent natural, semi-synthetic and synthetic analogues for treating cancer. Expand
Synthesis and Anti Tuberculostatic Activity of Novel 1,3,4‐Oxadiazole Derivatives
A series of novel 2,5-disubstituted 1,3,4-oxadiazole derivatives were synthesized and tested for their in vitro antimycobacterial activity. Some compounds showed interesting activity against a strainExpand
Design, synthesis and evaluation of novel 5,6-dimethoxy-1-oxo-2,3-dihydro-1H-2-indenyl-3,4-substituted phenyl methanone analogues.
TLDR
All the newly synthesized compounds were showing moderate to high AChE inhibitory activities, with compound 5,6-dimethoxy-1-oxo-2,3-dihydro-1H-2-indenyl-3,4,5-trimethoxyphenylmethanone producing significant activities. Expand
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