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pamamycin

National Institutes of Health

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Macrolides

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2010
2010
An enantioselective convergent route to pamamycin 621A.
An effective approach to the total synthesis of natural antibiotic pamamycin 621A is described, in which the stereogenic centers… 
2008
2008
Structure-activity Relationship of Pamamycins: Effect of Side Chain Length on Aerial Mycelium-inducing Activity
Two pamamycin homologues with different side chain lengths were isolated from Streptomyces sp. HKI-0118. Aerial mycelium-inducing… 
2005
2005
Nitrogen Incorporation in the Biosynthetic Pathway of the Nitrogen-containing Polyketide, Pamamycin in Streptomyces alboniger
The biosynthetic pathway of pamamycin (1), a nitrogen-containing polyketide, was investigated using blocked mutants of… 
2001
2001
Effects of N -Demethylation of Pamamycins on Aerial Mycelium-Inducing and Growth Inhibition Activities
Using a combination of ODS and NH 2 HPLCs, we isolated new pamamycin derivatives from the culture broth of Streptomyces alboniger… 
2000
2000
Catalytic, asymmetric synthesis of the C(1)(')-C(10)(') segment of pamamycin 621A.
[reaction--see text] This paper describes a catalytic, asymmetric approach to the C(1)(')-C(10)(') segment of pamamycin 621A. We… 
2000
2000
Catalytic, asymmetric synthesis of the C(1)(')-C(10)(') segment of pamamycin 621A.
[reaction--see text] This paper describes a catalytic, asymmetric approach to the C(1)(')-C(10)(') segment of pamamycin 621A. We… 
1999
1999
De-N-methylpamamycin-593A and B, new pamamycin derivatives isolated from Streptomyces alboniger.
homologues of pamamycinhaving different substituents at RX~R5and ranging in MWfrom 593 to 649, and confirmed that a change from… 
1998
1998
Discovery of new homologous pamamycins by mass spectrometry and post mortem inhibitory action on autolysis of chicken embryo chorioallantoic membrane blood vessels.
protonophoric agents10). The structural diversity of most of the published pamamycins has been ascribed to the substitution of… 
1994
1994
Formation of lipophilic ion pairs by derivatives of pamamycin
1981
1981
Mode of action of pamamycin in Staphylococcus aureus
Pamamycin was previously identified as a stimulator of aerial mycelium formation in Streptomyces alboniger and as a new… 
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