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Beetroot betalain inhibits peroxynitrite-mediated tyrosine nitration and DNA strand cleavage
Two major betalains, red-purple betacyanins and yellow betaxanthins, were isolated from red beetroots (Beta vulgaris L.), and their peroxynitrite (ONOO − ) scavenging capacity was investigated.Expand
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Comparisons of O-acylation and Friedel–Crafts acylation of phenols and acyl chlorides and Fries rearrangement of phenyl esters in trifluoromethanesulfonic acid: effective synthesis of optically
Abstract Reactions involving phenol derivatives and acyl chlorides have to be controlled for competitive O-acylations and C-acylations (Friedel–Crafts acylations and Fries rearrangements) in acidicExpand
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Structural Basis for the Formation of Acylalkylpyrones from Two β-Ketoacyl Units by the Fungal Type III Polyketide Synthase CsyB*
  • T. Mori, D. Yang, +4 authors I. Abe
  • Chemistry, Medicine
  • The Journal of Biological Chemistry
  • 7 January 2015
Background: CsyB from Aspergillus oryzae catalyzes the condensation of two β-ketoacyl units. Results: Crystal structures of CsyB revealed a novel pocket for accommodating the acetoacetyl-CoA starter.Expand
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A novel family of aromatic diazirines for photoaffinity labeling
A series of simple methods for modifying diazirines bearing an aromatic ring has been accomplished. This first versatile approach involving direct substitution on the aromatic ring of diazirines hasExpand
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Syntheses of Nitro-Substituted Aryl Diazirines. An Entry to Chromogenic Carbene Precursors for Photoaffinity Labeling
3-Phenyl-3-trifluoromethyl-diazirine derivatives with nitro and alkoxy substituents on their aromatic ring have been synthesized as carbene precursors for chromogenic detection of photolabeledExpand
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A carbene-generating biotinylated lactosylceramide analog as novel photoreactive substrate for GM3 synthase
Abstract A new biotinylated lactose derivative bearing a 14C-labeled phenyldiazirine was synthesized. A convenient approach based on avidin-biotin technology was successfully applied for GM3 synthaseExpand
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Hydrogen/deuterium exchange of cross-linkable α-amino acid derivatives in deuterated triflic acid
In this paper we report here a hydrogen/deuterium exchange (H/D exchange) of cross-linkable α-amino acid derivatives with deuterated trifluoromethanesulfonic acid (TfOD). H/D exchange with TfOD wasExpand
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Dehydrogenation of the NH-NH Bond Triggered by Potassium tert-Butoxide in Liquid Ammonia.
A novel strategy for the dehydrogenation of the NH-NH bond is disclosed using potassium tert-butoxide (tBuOK) in liquid ammonia (NH3 ) under air at room temperature. Its synthetic value is wellExpand
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