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pactimibe

National Institutes of Health

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Related topics

2 relations

Broader (1)

Indoleacetic Acids

Narrower (1)

pactimibe sulfate

Papers overview

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2012
2012
Inhibition of PCSK9 in familial hypercholesterolaemia
2010
2010
Novel acyl-CoA: cholesterol acyltransferase inhibitor: indoline-based sulfamide derivatives with low lipophilicity and protein binding ratio.
To find a novel acyl-CoA: cholesterol acyltransferase inhibitor, a series of sulfamide derivatives were synthesized and evaluated… 
2010
2010
Novel tetrahydroisoquinoline derivatives with inhibitory activities against acyl-CoA: cholesterol acyltransferase and lipid peroxidation.
To find a novel acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor with anti-lipid peroxidative activity, a series of… 
2008
2008
CYP2D6-Mediated Metabolism of a Novel Acyl Coenzyme A:Cholesterol Acyltransferase Inhibitor, Pactimibe, and Its Unique Plasma Metabolite, R-125528
Pactimibe sulfate is a novel acyl coenzyme A:cholesterol acyltransferase inhibitor. We conducted metabolic studies of pactimibe… 
2007
2007
Using eflucimibe for the preparation of a medicament for preventing or treating a disease due to a dysfunction of the sebaceous glands in humans or animals
The present invention relates to the use of at least one compound selected from (S) -2-dodecylsulfanyl-N- (4-hydroxy-2,3,5… 
2006
2006
Importance of acyl-coenzyme A:cholesterol acyltransferase 1/2 dual inhibition for anti-atherosclerotic potency of pactimibe.
2006
2006
Pactimibe stabilizes atherosclerotic plaque through macrophage acyl-CoA:cholesterol acyltransferase inhibition in WHHL rabbits.
2006
2006
Multiple mechanisms of hypocholesterolemic action of pactimibe, a novel acyl-coenzyme A:cholesterol acyltransferase inhibitor.
2006
2006
Abstract 1195: Proatherogenic Impact of the ACAT Inhibitor Pactimibe in Patients with Coronary Artery Disease and Multiple Risk Factors: Insights from the ACTIVATE study
2005
2005
Pactimibe for CAD may cause disease progression
  • 2005
  • Corpus ID: 195119147
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