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oxalylglycine

Known as: glycine, N-(carboxycarbonyl)-, oxaloglycine, N-(carboxycarbonyl)glycine 
 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Amino Acids, Dicarboxylic
dimethyloxalylglycine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
A novel effect of DMOG on cell metabolism: direct inhibition of mitochondrial function precedes HIF target gene expression.
Abnormal accumulation of oncometabolite fumarate and succinate is associated with inhibition of mitochondrial function and… Expand
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2015
2015
The broad spectrum 2-oxoglutarate oxygenase inhibitor N-oxalylglycine is present in rhubarb and spinach leaves.
2-Oxoglutarate (2OG) and ferrous iron dependent oxygenases are involved in many biological processes in organisms ranging from… Expand
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Highly Cited
2010
Highly Cited
2010
Design, synthesis, enzyme-inhibitory activity, and effect on human cancer cells of a novel series of jumonji domain-containing protein 2 histone demethylase inhibitors.
Selective inhibitors of Jumonji domain-containing protein (JMJD) histone demethylases are candidate anticancer agents as well as… Expand
Highly Cited
2009
Highly Cited
2009
Synthesis and activity of N-oxalylglycine and its derivatives as Jumonji C-domain-containing histone lysine demethylase inhibitors.
N-Oxalylglycine (NOG) derivatives were synthesized, and their inhibitory effect on histone lysine demethylase activity was… Expand
Highly Cited
2008
Highly Cited
2008
2-Oxoglutarate-dependent oxygenases control hepcidin gene expression.
BACKGROUND/AIMS Hepcidin is a liver-produced hormone that regulates systemic iron homeostasis. Hepcidin expression is stimulated… Expand
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1999
1999
Ultrastructural localisation and further biochemical characterisation of prolyl 4-hydroxylase from Phaseolus vulgaris: comparative analysis.
Prolyl 4-hydroxylase (EC 1.14.11.2), the enzyme responsible for the post-translational hydroxylation of peptide proline, has been… Expand
Highly Cited
1994
Highly Cited
1994
Inhibition of prolyl 4-hydroxylase by oxalyl amino acid derivatives in vitro, in isolated microsomes and in embryonic chicken tissues.
The potency of oxalyl amino acid derivatives as inhibitors of prolyl 4-hydroxylase was studied in vitro, in isolated microsomes… Expand
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1988
1988
Isotope effect studies of the chemical mechanism of pig heart NADP isocitrate dehydrogenase.
The catalytic mechanism of porcine heart NADP isocitrate dehydrogenase has been investigated by use of the variation of deuterium… Expand
1984
1984
Thermodynamic interactions in the glutamate dehydrogenase-NADPH-oxalylglycine complex.
The enzyme-reduced coenzyme-alpha-ketoglutarate ternary complex is a critical intermediate in the glutamate dehydrogenase… Expand
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Highly Cited
1980
Highly Cited
1980
Kinetic mechanism of glutamate dehydrogenase.
Initial velocity patterns and dead-end inhibition studies with oxalylglycine suggest that the addition of NADPH, keto acid, and… Expand
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