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oudenone

Known as: (S)-2-(4,5-dihydro-5-propyl-2(3H)- furylidene)-1,3-cyclopentanedione 
 
National Institutes of Health

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Cyclopentanes

Papers overview

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2006
2006
O A NEW MICROBIAL PRODUCT , OUDENONE , INHIBITING TYROSINE HYDROXYLASE
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  • 2006
Sir: Considering the ability of microorganisms to produce various types of compounds, we undertook a systematic study of specific… Expand
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2000
2000
Studies on the biosynthesis of oudenone and verucopeptin
The biosynthesis of the fungal metabolite oudenone ( 67 ) was investigated. The I-diketone ( 70 ) was synthesized and shown to be… Expand
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1999
1999
Studies on the Biosynthesis of the Fungal Metabolite Oudenone. 2. Synthesis and Enzymatic Cyclization of an alpha-Diketone, Open-Chain Precursor into Oudenone in Cultures of Oudemansiella radicata.
The alpha-diketone 4 was shown to be the open-chain biosynthetic precursor of the fungal metabolite oudenone (1a and 1b). Intact… Expand
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1993
1993
The biosynthesis of oudenone, a hypotensive agent from oudemansiella radicata
 
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1982
1982
Inhibition of phenylalanine hydroxylase, a pterin-requiring monooxygenase, by oudenone and its derivatives.
Phenylalanine hydroxylase was shown to be inhibited by oudenone and its derivatives in vitro. At a concentration of 2.3 x 10(-3… Expand
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1976
1976
Pharmacodynamic actions of (S)-2-[4,5-dihydro-5-propyl-2-(3H)-furylidene]-1,3-cyclopentanedione (oudenone).
The pharmacodynamic actions of (S)-2-[4,5-dihydro-5-propyl-2(3H)-furylidene]-1,3-cyclopentanedione (oudenone) were studied in… Expand
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Review
1973
Review
1973
Chemistry of enzyme inhibitors of microbial origin.
Study of antibiotics has furnished interesting materials to chemistry of natural products. I initiated the screening study of… Expand
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1973
1973
Catecholamine synthetic enzymes of spontaneously hypertensive rats and microbial hypotensive products
Summary1.Oudenone, an inhibitor of tyrosine hydroxylase, and fasaric acid, an inhibitor of dopamine-β-hydroxylase, both newly… Expand
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1972
1972
6 SYNTHETIC STUDY OF OUDENONE AND RELATED HOMOLOGUES, TYROSINE HYDROXYLASE INHIBITORS
 
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1971
1971
Oudenone, a novel tyrosine hydroxylase inhibitor from microbial origin.
 
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