Skip to search formSkip to main contentSkip to account menu

oroidin

Known as: 1H-Pyrrole-2-carboxamide, N-(3-(2-amino-1H-imidazol-4-yl)-2-propenyl)-4,5-dibromo-, (E)- 
National Institutes of Health

Related topics

Related topics

2 relations

Narrower (1)

7-(15)N-oroidin

Broader (1)

Pyrroles

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Antimicrobial Activity of the Marine Alkaloids, Clathrodin and Oroidin, and Their Synthetic Analogues
Marine organisms produce secondary metabolites that may be valuable for the development of novel drug leads as such and can also… 
2012
2012
Palau'amine and related oroidin alkaloids dibromophakellin and dibromophakellstatin inhibit the human 20S proteasome.
We report herein that the oroidin-derived alkaloids palau'amine (1), dibromophakellin (2), and dibromophakellstatin (3) inhibit… 
2010
2010
Synthesis of 7-(15)N-Oroidin and evaluation of utility for biosynthetic studies of pyrrole-imidazole alkaloids by microscale (1)H-(15)N HSQC and FTMS.
Numerous marine-derived pyrrole-imidazole alkaloids (PIAs), ostensibly derived from the simple precursor oroidin, 1a, have been… 
2009
2009
Amide isosteres of oroidin: assessment of antibiofilm activity and C. elegans toxicity.
The synthesis and antibiofilm activities of sulfonamide, urea, and thiourea oroidin analogues are described. The most active… 
Highly Cited
2008
Highly Cited
2008
Inhibition and dispersion of Pseudomonas aeruginosa biofilms with reverse amide 2-aminoimidazole oroidin analogues.
The marine alkaloid oroidin along with a small library of reverse amide (RA) 2-aminoimidazoles were synthesized and assayed for… 
Highly Cited
2008
Highly Cited
2008
Synthesis and Screening of an Oroidin Library against Pseudomonas aeruginosa Biofilms
A 50‐compound library based on the marine natural product oroidin was synthesized and assayed for anti‐biofilm activity against… 
2006
2006
Direct access to marine pyrrole-2-aminoimidazoles, oroidin, and derivatives, via new acyl-1,2-dihydropyridin intermediates.
[reaction: see text] A short synthesis of the C(11)N(5) oroidin derivatives is reported. The key step of the strategy is a one… 
Highly Cited
2004
Highly Cited
2004
Brominated pyrrole alkaloids from marine Agelas sponges reduce depolarization-induced cellular calcium elevation.
Highly Cited
2000
Highly Cited
2000
Structure–Activity Relationship of Inhibition of Fish Feeding by Sponge-derived and Synthetic Pyrrole–Imidazole Alkaloids
We investigated the relationship between the structures of pyrrole-containing alkaloids from marine sponges of the genus Agelas… 
Highly Cited
1993
Highly Cited
1993
Agelastatin a, a new skeleton cytotoxic alkaloid of the oroidin family. Isolation from the axinellid sponge Agelas dendromorpha of the coral sea
Agelastatin A, isolated from the axinellid sponge Agelas dendromorpha of the Coral Sea, is a new-skeleton alkaloid with… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)