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oridonin

Known as: lasidonin 
National Institutes of Health

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1 relation

Broader (1)

Diterpenes, Kaurane

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Oridonin ameliorates lipopolysaccharide/D-galactosamine-induced acute liver injury in mice via inhibition of apoptosis.
We investigated the protective effects exerted by oridonin, the main active constituent of the Chinese medicinal herb… 
2017
2017
Oridonin inhibits migration, invasion, adhesion and TGF-β1-induced epithelial-mesenchymal transition of melanoma cells by inhibiting the activity of PI3K/Akt/GSK-3β signaling pathway.
Epithelial-mesenchymal transition (EMT) has been reported to play pivotal roles in tumor invasion and metastasis. Inhibition of… 
2015
2015
Targeting TRAF3 Downstream Signaling Pathways in B cell Neoplasms
B cell neoplasms comprise >50% of blood cancers. However, many types of B cell malignancies remain incurable. Identification and… 
Review
2014
Review
2014
Oridonin, a promising antitumor natural product in the chemotherapy of hematological malignancies.
Oridonin, an ent-kaurane diterpenoid mainly extracted from Chinese medical plant Rabdosia rubescens and some related species, has… 
2011
2011
Synthesis and Anti-tumor Activity of 14-O-Derivatives of Natural Oridonin
Abstract Aim To synthesize novel 14- O -derivatives of natural oridonin and evaluate their anti-tumor activity. Methods Different… 
2010
2010
A novel analysis method for diterpenoids in rat plasma by liquid chromatography-electrospray ionization mass spectrometry.
2007
2007
Inactivation of ras and changes of mitochondrial membrane potential contribute to oridonin-induced autophagy in a431 cells.
We have previously shown that oridonin isolated from Rabdosia rubescens augmented apoptosis while inhibiting autophagy within 24… 
2006
2006
Fas/FasL signaling allows extracelluar-signal regulated kinase to regulate cytochrome c release in oridonin-induced apoptotic U937 cells.
Previously, we found that human histocytic lymphoma U937 cells possessed high susceptibility to oridonin-induced cell death, but… 
2005
2005
Activation of phosphoinositide 3-kinase, protein kinase C, and extracellular signal-regulated kinase is required for oridonin-enhanced phagocytosis of apoptotic bodies in human macrophage-like U937…
Our previous study showed that oridonin isolated from Rabdosia rubescens enhanced phagocytosis of apoptotic cells by macrophage… 
2004
2004
Oridonin induces apoptosis of HeLa cells via altering expression of Bcl-2/Bax and activating caspase-3/ICAD pathway.
AIM To study the mechanisms by which oridonin inhibited HeLa cell growth in vitro. METHODS Viability of oridonin-induced HeLa… 
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