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Diterpenes, Kaurane

Known as: Diterpenes, Kaurane [Chemical/Ingredient], Kaurane Diterpenes, Kauranes 
A group of DITERPENES cyclized into four rings.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1966-2017
05101519662017

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16,17-exo-epoxide-oridonin16-kauren-19-oic acid19-beta-D-glucopyranosyl 6,7-dihydroxy kaurenoate7,11,16,17-tetrahydroxykaurane
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In BloodProcess of secretionantagonists & inhibitorschemical synthesis
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Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Diterpenes, Kaurane
physiological aspects
In Blood
chemical synthesis
stevioside
oridonin

Papers overview

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2010
2010
Coffee induces expression of glucuronosyltransferases by the aryl hydrocarbon receptor and Nrf2 in liver and stomach.
BACKGROUND & AIMS Coffee is one of the most widely consumed beverages worldwide. Epidemiologic data indicate that coffee… (More)
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2008
2008
Induction of cancer chemopreventive enzymes by coffee is mediated by transcription factor Nrf2. Evidence that the coffee-specific diterpenes cafestol and kahweol confer protection against acrolein.
Mice fed diets containing 3% or 6% coffee for 5 days had increased levels of mRNA for NAD(P)H:quinone oxidoreductase 1 (NQO1) and… (More)
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2007
2007
Kaurane diterpenes protect against apoptosis and inhibition of phagocytosis in activated macrophages.
BACKGROUND AND PURPOSE The kaurane diterpenes foliol and linearol are inhibitors of the activation of nuclear factor kappaB, a… (More)
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2006
2006
PTP1B inhibitory activity of kaurane diterpenes isolated from Siegesbeckia glabrescens.
Protein tyrosine phosphatase 1B (PTP1B) is considered as a therapeutic target for the treatment of diabetes and obesity. In our… (More)
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2005
2005
Neoclerodane diterpenes as a novel scaffold for mu opioid receptor ligands.
Structural modification of salvinorin A, the active component of Salvia divinorum, has resulted in the synthesis of novel… (More)
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2002
2002
Kaurane diterpene, kamebakaurin, inhibits NF-kappa B by directly targeting the DNA-binding activity of p50 and blocks the expression of antiapoptotic NF-kappa B target genes.
Kaurane diterpenes have been identified from numerous medicinal plants, which have been used for treatment of inflammation and… (More)
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2001
2001
Protective effects of coffee diterpenes against aflatoxin B1-induced genotoxicity: mechanisms in rat and human cells.
The coffee-specific diterpenes cafestol and kahweol (C + K) have been reported to be anticarcinogenic in several animal models… (More)
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2001
2001
Kaurane diterpenes from Isodon japonicus inhibit nitric oxide and prostaglandin E2 production and NF-kappaB activation in LPS-stimulated macrophage RAW264.7 cells.
A methanolic extract of the whole plant of Isodon japonicus (Labiatae) showed potent inhibition on the LPS-induced nitric oxide… (More)
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1997
1997
Analysis of the content of the diterpenes cafestol and kahweol in coffee brews.
The diterpenes cafestol and kahweol have been implicated as the components in boiled coffee responsible for its… (More)
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1979
1979
Mechanism of tumor promoter inhibition of cellular binding of epidermal growth factor.
In previous studies we demonstrated that the tumor-promoting agent 12-O-tetradecanoyl phorbol 13-acetate (TPA) and related… (More)
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