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organic cation transport

The directed movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore… Expand
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
PURPOSE Knowledge of transporters responsible for the renal secretion of creatinine is key to a proper interpretation of serum… Expand
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Highly Cited
2005
Highly Cited
2005
Cis-platin is an effective anti-neoplastic agent, but it is also highly nephrotoxic. Here, we clearly identify the human organic… Expand
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Highly Cited
2005
Highly Cited
2005
Many endogenous compounds and xenobiotics are organic cations that rely on polyspecific organic cation transporters (OCTs) to… Expand
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Highly Cited
2001
Highly Cited
2001
The kidney, and more specifically the proximal tubule, is the main site of elimination of cationic endogenous metabolites and… Expand
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2001
2001
Previous inhibition studies with taurocholate and cardiac glycosides suggested the presence of separate uptake systems for small… Expand
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Highly Cited
2000
Highly Cited
2000
Rat (r) OCT2 was identified as the second member of the organic cation transporter (OCT) family, and is predominantly expressed… Expand
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2000
2000
Organic cation transporters play an important role in the absorption, distribution, and elimination of clinical agents, toxic… Expand
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Highly Cited
1999
Highly Cited
1999
The organic cation transporter (OCT) mediates translocation of various cationic molecules including drugs, toxins and endogenous… Expand
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Highly Cited
1998
Highly Cited
1998
Recently, a polyspecific organic cation transporter, hOCT1, was cloned from human liver. To date, limited studies examining the… Expand
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Highly Cited
1997
Highly Cited
1997
Polyspecific organic cation transporters in the liver mediate the elimination of a wide array of endogenous amines and… Expand
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