C. Lehr

Publications521
h-index82
Citations23,827
Highly Influential Citations568
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In vitro evaluation of mucoadhesive properties of chitosan and some other natural polymers
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Diverse Applications of Nanomedicine
TLDR
An overview of recent developments in nanomedicine is provided and the current challenges and upcoming opportunities for the field are highlighted and translation to the clinic is highlighted.
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Nanoparticles--an efficient carrier for drug delivery into the hair follicles.
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Size-Dependent Bioadhesion of Micro- and Nanoparticulate Carriers to the Inflamed Colonic Mucosa
TLDR
The use of submicron-sized carriers holds promise for the targeted delivery of drugs to the inflamed colonic mucosal areas in inflammatory bowel disease.
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Preparation and characterization of cationic PLGA nanospheres as DNA carriers.
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Chitosan-coated PLGA nanoparticles for DNA/RNA delivery: effect of the formulation parameters on complexation and transfection of antisense oligonucleotides.
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Mucus as a barrier to lipophilic drugs.
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Effect of cationic lipid and matrix lipid composition on solid lipid nanoparticle-mediated gene transfer.
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The human epidermis models EpiSkin, SkinEthic and EpiDerm: an evaluation of morphology and their suitability for testing phototoxicity, irritancy, corrosivity, and substance transport.
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A three-dimensional coculture of enterocytes, monocytes and dendritic cells to model inflamed intestinal mucosa in vitro.
TLDR
The 3D coculture system may serve as a valuable tool for developing drugs and formulations for the treatment of inflammatory bowel diseases, as well as for studying the interaction of xenobiotics and nanoparticles with the intestinal epithelial barrier in the state of inflammation.
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