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omeprazole sulfone

Known as: omeprazole sulphone 
National Institutes of Health

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2 relations

Broader (1)

Omeprazole
analogs & derivatives

Papers overview

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2011
2011
Chiral assay of omeprazole and metabolites and its application to a pharmacokinetics related to CYP2C19 genotypes.
2009
2009
CYP2C19 haplotypes in Koreans as a marker of enzyme activity evaluated with omeprazole
Background and objective:  CYP2C19 is clinically important in Korea because of the relatively high incidence of poor metabolizers… 
2008
2008
Investigation of the in vivo activity of CYP3A in Brazilian volunteers: comparison of midazolam and omeprazole as drug markers
ObjectiveThis study compares midazolam with omeprazole as marker drugs for the evaluation of CYP3A activity in nine healthy self… 
2007
2007
Simultaneous determination of omeprazole, hydroxyomeprazole and omeprazole sulphone in human plasma by isocratic HPLC-DAD: application to the phenotyping of CYP2C19 and CYP3A4 in brazilian volunteers
A simple HPLC-DAD method using a reverse phase column and isocratic elution for the simultaneous determination of omeprazole (OME… 
2006
2006
Sensitive determination of omeprazole and its two main metabolites in human plasma by column-switching high-performance liquid chromatography: application to pharmacokinetic study in relation to…
2005
2005
Effect of cimetidine and phenobarbital on metabolite kinetics of omeprazole in rats
Omeprazole (OMP) is a proton pump inhibitor used as an oral treatment for acid-related gastrointestinal disorders. In the liver… 
2004
2004
IS 17α-ETHINYL ESTRADIOL AN INHIBITOR OF CYTOCHROME P450 2C19?
We have read with great interest the increasing number of publications reporting that oral contraceptive (OC)[1][1] formulations… 
2002
2002
Phenotype of CYP2C19 and CYP3A4 by determination of omeprazole and its two main metabolites in plasma using liquid chromatography with liquid-liquid extraction.
2000
2000
Probing CYP2C19 and CYP3A4 activities in Chinese liver microsomes by quantification of 5-hydroxyomeprazole and omeprazole sulphone.
AIM To develop an analytical method for simultaneous quantification of 5-hydroxyomeprazole (5-OH-OP) and omeprazole sulfone (OPS… 
1999
1999
Stereospecific analysis of omeprazole supports artemisinin as a potent inducer of CYP2C19
Abstract— The purpose of the study was to determine the enantiomer pharmacokinetics of omeprazole and 5‐hydroxy‐omeprazole before… 
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