Omeprazole

Known as: omeprazole product, 1H-Benzimidazole, 5-methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridinyl)methyl)sulfinyl)-, OMEP 
A benzimidazole with selective and irreversible proton pump inhibition activity. Omeprazole forms a stable disulfide bond with the sulfhydryl group… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1957-2018
020040019572017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
BACKGROUND Gastrointestinal complications are an important problem of antithrombotic therapy. Proton-pump inhibitors (PPIs) are… (More)
  • table 1
  • figure 1
  • table 2
  • figure 2
  • table 3
Is this relevant?
Highly Cited
2008
Highly Cited
2008
OBJECTIVES This trial sought to assess the influence of omeprazole on clopidogrel efficacy. BACKGROUND Clopidogrel has proved… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2005
Highly Cited
2005
BACKGROUND & AIMS Data indicate that cyclooxygenase-2-specific inhibitors cause less gastroduodenal mucosal damage than… (More)
Is this relevant?
Highly Cited
2004
Highly Cited
2004
The human clearance of proton pump inhibitors (PPIs) of the substituted benzimidazole class is conducted primarily by the hepatic… (More)
  • figure 1
  • table 1
  • table 2
  • figure 2
Is this relevant?
Highly Cited
2002
Highly Cited
2002
BACKGROUND Current guidelines recommend that patients at risk for ulcer disease who require treatment for arthritis receive… (More)
Is this relevant?
Highly Cited
2001
Highly Cited
2001
BACKGROUND & AIMS Nonacid reflux may explain symptoms in acid-suppressed patients. Simultaneous intraesophageal impedance and pH… (More)
Is this relevant?
Highly Cited
1998
Highly Cited
1998
BACKGROUND Misoprostol is effective for ulcers associated with the use of nonsteroidal antiinflammatory drugs (NSAIDs) but is… (More)
Is this relevant?
Highly Cited
1998
Highly Cited
1998
BACKGROUND Suppressing acid secretion is thought o reduce the risk of ulcers associated with regular use of nonsteroidal… (More)
Is this relevant?
Highly Cited
1993
Highly Cited
1993
where fk is the current approximation, and Rk f the current residual (error). Using initial values of Ro f = f , fo = 0, and k… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1988
Highly Cited
1988
We have studied the response of erosive or ulcerative esophagitis to treatment with omeprazole and its subsequent relapse on… (More)
Is this relevant?