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Omeprazole

Known as: omeprazole product, 1H-Benzimidazole, 5-methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridinyl)methyl)sulfinyl)-, OMEP 
A benzimidazole with selective and irreversible proton pump inhibition activity. Omeprazole forms a stable disulfide bond with the sulfhydryl group… 
National Institutes of Health

Related topics

Related topics

33 relations

Broader (2)

Anti-Ulcer AgentProton Pump Inhibitors
Aspirin 325 MG / Omeprazole 40 MG Delayed Release Oral Tablet [Yosprala]CYP2C19 protein, humanEsomeprazoleGastric ulcer

Narrower (8)

H168/68PrilosecYospralaZegerid

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Running title page Running title : Functional stability of CYP P 450 enzymes in HepaRG cells
INSERM U620, Rennes, France (SA, AG), Université de Rennes 1, Faculté des Sciences Pharmaceutiques et Biologiques, Rennes, France… 
Review
2007
Review
2007
CYP1A Induction and Human Risk Assessment: An Evolving Tale of in Vitro and in Vivo Studies
CYP1A1 and 1A2 play critical roles in the metabolic activation of carcinogenic polycyclic aromatic hydrocarbons (PAHs) and… 
Highly Cited
2006
Highly Cited
2006
Antiulcerogenic and ulcer healing effects of Solanum nigrum (L.) on experimental ulcer models: possible mechanism for the inhibition of acid formation.
Review
1999
Review
1999
Temporal variability in living deep-sea benthic foraminifera: a review
Highly Cited
1999
Highly Cited
1999
KTP laser destruction of dysplasia and early cancer in columnar-lined Barrett's esophagus.
Highly Cited
1999
Highly Cited
1999
Oxidation of troglitazone to a quinone-type metabolite catalyzed by cytochrome P-450 2C8 and P-450 3A4 in human liver microsomes.
Troglitazone, a new oral antidiabetic drug, is reported to be mostly metabolized to its conjugates and not to be oxidized by… 
Highly Cited
1999
Highly Cited
1999
OSPF Optimized Multipath (OSPF-OMP)
Highly Cited
1998
Highly Cited
1998
A new genetic defect in human CYP2C19: mutation of the initiation codon is responsible for poor metabolism of S-mephenytoin.
The 4'-hydroxylation of the S-enantiomer of the anticonvulsant drug mephenytoin exhibits a genetic polymorphism in humans. This… 
Highly Cited
1995
Highly Cited
1995
Interphenotype differences in disposition and effect on gastrin levels of omeprazole--suitability of omeprazole as a probe for CYP2C19.
1. Fourteen healthy Swedish Caucasian subjects were given 20 mg of omeprazole orally each morning for 8 days. The subjects… 
Highly Cited
1990
Highly Cited
1990
Characterization of the protective capacity and immunogenicity of the 69-kD outer membrane protein of Bordetella pertussis
Immunization with the 69-kD outer membrane protein (OMP) of Bordetella pertussis protected neonatal mice against lethal… 
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