Esomeprazole

Known as: Esomeprazolum, Ésoméprazole, (-)-omeprazole 
The S-isomer of omeprazole, with gastric proton pump inhibitor activity. In the acidic compartment of parietal cells, esomeprazole is protonated and… (More)
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
BACKGROUND Clopidogrel is activated by CYP2C19, which also metabolizes proton pump inhibitors (PPI). As proton pump inhibitors… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Gastroesophageal reflux is common among patients with asthma but often causes mild or no symptoms. It is not known… (More)
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Highly Cited
2009
Highly Cited
2009
Both gastroesophageal reflux disease and allergy/atopy have been implicated in the pathogenesis of eosinophilic esophagitis (EoE… (More)
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Highly Cited
2006
Highly Cited
2006
OBJECTIVE To evaluate the efficacy of acid-suppressive therapy with the proton pump inhibitor esomeprazole on the signs and… (More)
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Highly Cited
2006
Highly Cited
2006
OBJECTIVES:Proton pump inhibitors reduce ulcer recurrence in non-steroidal anti-inflammatory drug (NSAID) users, but their impact… (More)
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Highly Cited
2004
Highly Cited
2004
The human clearance of proton pump inhibitors (PPIs) of the substituted benzimidazole class is conducted primarily by the hepatic… (More)
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Highly Cited
2003
Highly Cited
2003
OBJECTIVES:Proton pump inhibitors owe their clinical efficacy to their ability to suppress gastric acid production. The objective… (More)
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Highly Cited
2002
Highly Cited
2002
OBJECTIVES: Esomeprazole, the S isomer of omeprazole, has been shown to have higher healing rates of erosive esophagitis than… (More)
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Highly Cited
2001
Highly Cited
2001
OBJECTIVE:In patients with gastroesophageal reflux disease (GERD), esomeprazole, the S-isomer of omeprazole, has demonstrated… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND The pharmacologic profile of the new proton pump inhibitor esomeprazole has demonstrated advantages over omeprazole… (More)
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