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Esomeprazole

Known as: Esomeprazolum, Ésoméprazole, (-)-omeprazole 
The S-isomer of omeprazole, with gastric proton pump inhibitor activity. In the acidic compartment of parietal cells, esomeprazole is protonated and… Expand
National Institutes of Health

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Highly Cited
2011
Highly Cited
2011
CONTEXT Gastroesophageal reflux disease (GERD) is a chronic, relapsing disease with symptoms that have negative effects on daily… Expand
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Gastroesophageal reflux is common among patients with asthma but often causes mild or no symptoms. It is not known… Expand
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Clopidogrel is activated by CYP2C19, which also metabolizes proton pump inhibitors (PPI). As proton pump inhibitors… Expand
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Highly Cited
2006
Highly Cited
2006
OBJECTIVE To evaluate the efficacy of acid-suppressive therapy with the proton pump inhibitor esomeprazole on the signs and… Expand
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Highly Cited
2006
Highly Cited
2006
OBJECTIVES:Proton pump inhibitors reduce ulcer recurrence in non-steroidal anti-inflammatory drug (NSAID) users, but their impact… Expand
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Highly Cited
2006
Highly Cited
2006
RATIONALE Gastroesophageal reflux disease (GERD) is common in patients with asthma, suggesting an interaction between the two… Expand
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Concurrent therapy with a proton-pump inhibitor is a standard treatment for patients receiving aspirin who are at risk… Expand
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Highly Cited
2004
Highly Cited
2004
The human clearance of proton pump inhibitors (PPIs) of the substituted benzimidazole class is conducted primarily by the hepatic… Expand
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Review
2003
Review
2003
Thirty years ago, disorders associated with inappropriate levels of gastric acid were a major problem for which treatment options… Expand
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Highly Cited
2002
Highly Cited
2002
OBJECTIVES: Esomeprazole, the S isomer of omeprazole, has been shown to have higher healing rates of erosive esophagitis than… Expand
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