omacetaxine mepesuccinate

Known as: (2'R,3S,4S,5R)-(-)-homoharringtonine, Cephalotaxine, 4-Methyl 2-hydroxy-2-(4-hydroxy-4-methylpentyl)butanedioate (Ester), Homoharringtonin 
A semisynthetic formulation of the cytotoxic plant alkaloid homoharringtonine isolated from the evergreen tree Cephalotaxus with potential… (More)

Topic mentions per year

Topic mentions per year

1951-2018
010020030019512017

Papers overview

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2012
2012
Chronic myeloid leukemia (CML) patients with the BCR-ABL T315I mutation do not benefit from therapy with currently approved… (More)
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Highly Cited
2009
Highly Cited
2009
n engl j med 361;9 nejm.org august 27, 2009 932 evidence of the efficacy of bevacizumab in patients with HHT. Both cases also… (More)
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Highly Cited
2009
Highly Cited
2009
Human colon cancers often start as benign adenomas through loss of APC, leading to enhanced beta CATENIN (beta CAT)/TCF function… (More)
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Highly Cited
2004
Highly Cited
2004
The 'malnutrition universal screening tool' ('MUST') for adults has been developed for all health care settings and patient… (More)
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Highly Cited
2002
Highly Cited
2002
We performed genetic association studies in a population-based breast cancer case-control study analysing polymorphisms in genes… (More)
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Highly Cited
2000
Highly Cited
2000
Hereditary Hemorrhagic Telangiectasia (HHT) is easily recognized in individuals displaying the classical triad of epistaxis… (More)
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Highly Cited
1995
Highly Cited
1995
Considerable e ort has been directed recently to develop asymptotically minimax methods in problems of recovering in nite… (More)
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Highly Cited
1995
Highly Cited
1995
A number of lines of evidence suggest that red wine may be more effective than other alcoholic beverages in decreasing the risk… (More)
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Highly Cited
1994
Highly Cited
1994
Extracellular signaling proteins encoded by the hedgehog (hh) multigene family are responsible for the patterning of a variety of… (More)
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1961
Highly Cited
1961
Van der Pol's equation for a relaxation oscillator is generalized by the addition of terms to produce a pair of non-linear… (More)
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