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Harringtonines

Known as: Alkaloids, Cephalotaxus, Cephalotaxus Alkaloids, Cephalotaxine Alkaloids 
Tetracyclic spiro-BENZAZEPINES isolated from the seeds of CEPHALOTAXUS. They are esters of the alkaloid cephalotaxine and may be effective as… 
National Institutes of Health

Related topics

Related topics

26 relations

Narrower (15)

11-hydroxycephalotaxine4'-desmethylhomoharringtonineHH07AHVF protocol

Broader (3)

AlkaloidsAntineoplastic AgentsAntineoplastic Agents, Phytogenic
In BloodProcess of secretionagonistsantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Alkaloids from Cephalotaxus lanceolata and Their Cytotoxicities
A phytochemical investigation of the branches and leaves of Cephalotaxus lanceolata resulted in the isolation of three new… 
2012
2012
Antioxidant activities and phenolic constituents of Cephalotaxus oliveri Mast. aerial parts
The present study was to analyze the antioxidant activity and the responsible chemical constituents in Cephalotaxus oliveri… 
2008
2008
Homo-Harringtonine (Omacetaxine mepesuccinate) Induces a Dramatic and Sustained Reduction of BCR-ABLT315I mutated Transcripts in Chronic Phase Chronic Myelogenous Leukemia Patients Resistant to…
The treatment of chronic myelogenous leukemia (CML) has been revolutionized by the introduction of tyrosine kinase inhibitors in… 
2004
2004
[Proteome analysis of apoptotic K562 cells induced by harringtonine].
OBJECTIVE To screen and identify apoptosis related proteins and explore the mechanism of harringtonine (HT)-induced K562 cells… 
Highly Cited
2003
Highly Cited
2003
Translation Inhibitors Sensitize Prostate Cancer Cells to Apoptosis Induced by Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) by Activating c-Jun N-terminal Kinase*
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces apoptosis in several human tumors both in vitro and in… 
Highly Cited
2001
Highly Cited
2001
An approach toward isoindolobenzazepines using the ammonium ylide/Stevens.
Ammonium ylides derived from the Cu(II)-catalyzed decomposition of alpha-diazo carbonyls tethered to tertiary amines underwent a… 
2000
2000
Stability-indicating LC assay of and impurity identification in homoharringtonine samples.
1977
1977
Antitumor alkaloids in callus cultures of Cephalotaxus harringtonia
1974
1974
Partial synthesis of harringtonine analogs.
Three analogs of harringtonine (II), an ester alkaloid which is active in the P-388 experimental leukemia system, were prepared… 
Highly Cited
1972
Highly Cited
1972
Deoxyharringtonine, a new antitumor alkaloid from Cephalotaxus: Structure and synthetic studies
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