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Harringtonines
Known as:
Alkaloids, Cephalotaxus
, Cephalotaxus Alkaloids
, Cephalotaxine Alkaloids
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Tetracyclic spiro-BENZAZEPINES isolated from the seeds of CEPHALOTAXUS. They are esters of the alkaloid cephalotaxine and may be effective as…
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National Institutes of Health
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Related topics
Related topics
26 relations
Narrower (15)
11-hydroxycephalotaxine
4'-desmethylhomoharringtonine
HH07A
HVF protocol
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Broader (3)
Alkaloids
Antineoplastic Agents
Antineoplastic Agents, Phytogenic
In Blood
Process of secretion
agonists
antagonists & inhibitors
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2018
Highly Cited
2018
Mesophyll Cells Are the Main Site of Abscisic Acid Biosynthesis in Water-Stressed Leaves1[OPEN]
S. McAdam
,
T. Brodribb
Plant Physiology
2018
Corpus ID: 13683408
Analysis of leaves from one angiosperm and four conifers where the mesophyll and vasculature can be mechanically separated…
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2016
2016
Mannolides A-C with an Intact Diterpenoid Skeleton Providing Insights on the Biosynthesis of Antitumor Cephalotaxus Troponoids.
Gang Ni
,
Hua Zhang
,
Yao-yue Fan
,
Hong-chun Liu
,
Jian Ding
,
J. Yue
Organic Letters
2016
Corpus ID: 26454101
Three new diterpenoids, mannolides A-C (1-3), and two new Cephalotaxus troponoids, 4 and 5, were isolated from Cephalotaxus…
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Highly Cited
2012
Highly Cited
2012
The ribosome profiling strategy for monitoring translation in vivo by deep sequencing of ribosome-protected mRNA fragments
Nicholas T. Ingolia
,
G. Brar
,
Silvi Rouskin
,
Anna M. McGeachy
,
J. Weissman
Nature Protocols
2012
Corpus ID: 205465397
Recent studies highlight the importance of translational control in determining protein abundance, underscoring the value of…
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Highly Cited
2011
Highly Cited
2011
Ribosome Profiling of Mouse Embryonic Stem Cells Reveals the Complexity and Dynamics of Mammalian Proteomes
Nicholas T. Ingolia
,
L. Lareau
,
J. Weissman
Cell
2011
Corpus ID: 8328474
Highly Cited
2001
Highly Cited
2001
An approach toward isoindolobenzazepines using the ammonium ylide/Stevens.
A. Padwa
,
L. Beall
,
C. K. Eidell
,
K. Worsencroft
Journal of Organic Chemistry
2001
Corpus ID: 24336156
Ammonium ylides derived from the Cu(II)-catalyzed decomposition of alpha-diazo carbonyls tethered to tertiary amines underwent a…
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Review
2001
Review
2001
Analytical approaches for traditional chinese medicines exhibiting antineoplastic activity.
T. Tsai
Journal of Chromatography B: Biomedical Sciences…
2001
Corpus ID: 12765707
Highly Cited
1999
Highly Cited
1999
Trichothecene Mycotoxins Trigger a Ribotoxic Stress Response That Activates c-Jun N-terminal Kinase and p38 Mitogen-activated Protein Kinase and Induces Apoptosis*
V. Shifrin
,
P. Anderson
Journal of Biological Chemistry
1999
Corpus ID: 8675631
The trichothecene family of mycotoxins inhibit protein synthesis by binding to the ribosomal peptidyltransferase site. Inhibitors…
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Highly Cited
1977
Highly Cited
1977
Inhibition of translation in eukaryotic systems by harringtonine.
M. Fresno
,
A. Jimenez
,
D. Vazquez
European Journal of Biochemistry
1977
Corpus ID: 24394360
The Cephalotaxus alkaloids harringtonine, homoharringtonine and isoharringtonine inhibit protein synthesis in eukaryotic cells…
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Highly Cited
1975
Highly Cited
1975
Harringtonine, an inhibitor of initiation of protein biosynthesis.
M. Huang
Molecular Pharmacology
1975
Corpus ID: 46688482
The Cephalotaxus alkaloid harringtonine inhibits protein biosynthesis in HeLa cells, intact rabbit reticulocytes, and…
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Highly Cited
1972
Highly Cited
1972
Deoxyharringtonine, a new antitumor alkaloid from Cephalotaxus: Structure and synthetic studies
K. Mikolajczak
,
R. G. Powell
,
C. Smith
1972
Corpus ID: 13752353
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