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Harringtonines

Known as: Alkaloids, Cephalotaxus, Cephalotaxus Alkaloids, Cephalotaxine Alkaloids 
Tetracyclic spiro-BENZAZEPINES isolated from the seeds of CEPHALOTAXUS. They are esters of the alkaloid cephalotaxine and may be effective as… 
National Institutes of Health

Related topics

Related topics

26 relations

Narrower (15)

11-hydroxycephalotaxine4'-desmethylhomoharringtonineHH07AHVF protocol

Broader (3)

AlkaloidsAntineoplastic AgentsAntineoplastic Agents, Phytogenic
In BloodProcess of secretionagonistsantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2018
Highly Cited
2018
Mesophyll Cells Are the Main Site of Abscisic Acid Biosynthesis in Water-Stressed Leaves1[OPEN]
Analysis of leaves from one angiosperm and four conifers where the mesophyll and vasculature can be mechanically separated… 
2016
2016
Mannolides A-C with an Intact Diterpenoid Skeleton Providing Insights on the Biosynthesis of Antitumor Cephalotaxus Troponoids.
Three new diterpenoids, mannolides A-C (1-3), and two new Cephalotaxus troponoids, 4 and 5, were isolated from Cephalotaxus… 
Highly Cited
2012
Highly Cited
2012
The ribosome profiling strategy for monitoring translation in vivo by deep sequencing of ribosome-protected mRNA fragments
Recent studies highlight the importance of translational control in determining protein abundance, underscoring the value of… 
Highly Cited
2011
Highly Cited
2011
Ribosome Profiling of Mouse Embryonic Stem Cells Reveals the Complexity and Dynamics of Mammalian Proteomes
Highly Cited
2001
Highly Cited
2001
An approach toward isoindolobenzazepines using the ammonium ylide/Stevens.
Ammonium ylides derived from the Cu(II)-catalyzed decomposition of alpha-diazo carbonyls tethered to tertiary amines underwent a… 
Review
2001
Review
2001
Analytical approaches for traditional chinese medicines exhibiting antineoplastic activity.
  • T. Tsai
  • Journal of Chromatography B: Biomedical Sciences…
  • 2001
  • Corpus ID: 12765707
Highly Cited
1999
Highly Cited
1999
Trichothecene Mycotoxins Trigger a Ribotoxic Stress Response That Activates c-Jun N-terminal Kinase and p38 Mitogen-activated Protein Kinase and Induces Apoptosis*
The trichothecene family of mycotoxins inhibit protein synthesis by binding to the ribosomal peptidyltransferase site. Inhibitors… 
Highly Cited
1977
Highly Cited
1977
Inhibition of translation in eukaryotic systems by harringtonine.
The Cephalotaxus alkaloids harringtonine, homoharringtonine and isoharringtonine inhibit protein synthesis in eukaryotic cells… 
Highly Cited
1975
Highly Cited
1975
Harringtonine, an inhibitor of initiation of protein biosynthesis.
  • M. Huang
  • Molecular Pharmacology
  • 1975
  • Corpus ID: 46688482
The Cephalotaxus alkaloid harringtonine inhibits protein biosynthesis in HeLa cells, intact rabbit reticulocytes, and… 
Highly Cited
1972
Highly Cited
1972
Deoxyharringtonine, a new antitumor alkaloid from Cephalotaxus: Structure and synthetic studies
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