ofatumumab

Known as: Ofatumumabum, immunoglobulin G1, anti-(human CD20 (antigen))(human monoclonal humax-CD20 heavy chain), disulfide with human monoclonal humax-CD20 kappa-chain, dimer 
A fully human, high-affinity IgG1 monoclonal antibody directed against the B cell CD20 cell surface antigen with potential antineoplastic activity… (More)
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
BACKGROUND In patients with chronic lymphoid leukemia (CLL) or small lymphocytic lymphoma (SLL), a short duration of response to… (More)
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Highly Cited
2014
Highly Cited
2014
OBJECTIVES We present the first study to explore safety and efficacy of the human CD20 monoclonal antibody ofatumumab in… (More)
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2014
2014
n engl j med 370;13 nejm.org march 27, 2014 1268 ing the trachea. However, this test is not infallible, and there are cases… (More)
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Highly Cited
2013
Highly Cited
2013
We report the first preclinical in vitro and in vivo comparison of GA101 (obinutuzumab), a novel glycoengineered type II CD20… (More)
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Highly Cited
2012
Highly Cited
2012
New treatments are required for rituximab-refractory follicular lymphoma (FL). In the present study, patients with rituximab… (More)
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Highly Cited
2011
Highly Cited
2011
Ofatumumab, the human CD20 monoclonal antibody that binds a distinct epitope from rituximab, has demonstrated clinical benefit as… (More)
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Highly Cited
2009
Highly Cited
2009
The CD20 mAb ofatumumab (OFA) is more effective than rituximab (RTX) in promoting complement-dependent cytotoxicity (CDC) of B… (More)
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Highly Cited
2008
Highly Cited
2008
Ofatumumab is a unique monoclonal antibody that targets a distinct small loop epitope on the CD20 molecule. Preclinical data show… (More)
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Highly Cited
2007
Highly Cited
2007
Safety and efficacy of the fully human anti-CD20 monoclonal antibody, ofatumumab, was analyzed in a multicenter dose-escalating… (More)
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Highly Cited
2005
Highly Cited
2005
OBJECTIVE Interleukin-15 (IL-15) is a proinflammatory, innate response cytokine that mediates pleiotropic effector function in… (More)
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