Arzerra
National Institutes of Health
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Abstract AKT plays a centralized role in tumor proliferation and survival and is aberrantly activated in chronic lymphocytic…
Ofatumumab (Arzerra®) is a human monoclonal antibody which binds specifically to CD20 on the surface of B cells. Thereby…
Chronic lymphocytic leukaemia (CLL) is a type of non-Hodgkin lymphoma that results from the transformation of B-lymphocytes in…
Aim: To rewiew the drugs‘ development and the breakthrough therapy for CLL, represented by ofatumumab (Arzerra®), obinutuzumab…
Patienten mit chronischer lymphatischer Leukämie (CLL), die therapierefraktär gegenüber Fludarabin und Alemtuzumab sind, haben…
Ofatumumab; Leucemia limfatica cronica; Revisio sistematica; Chronic lymphocytic leukaemia; Systematic review; Leucemia linfatica…
With the success of the anti-CD20 mAb rituximab in treating B-cell disorders from lymphoma through rheumatoid arthritis, anti…