nucleotide analog

 
National Institutes of Health

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Review
2014
Review
2014
Hepatitis B virus (HBV) polymerase and human immunodeficiency virus (HIV) reverse transcriptase are structurally related. However… (More)
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2009
2009
Nucleotide analog interference mapping (NAIM) is a powerful chemogenetic technique that rapidly identifies chemical groups… (More)
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2007
2007
OBJECTIVES The K65R mutation in HIV-1 reverse transcriptase (RT) decreases susceptibility to all approved nucleoside reverse… (More)
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Highly Cited
2006
Highly Cited
2006
Alzheimer disease is a neurological disorder that is characterized by the presence of fibrils and oligomers composed of the… (More)
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2004
2004
Comparative kinetic and structural analyses of a variety of polymerases have revealed both common and divergent elements of… (More)
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Highly Cited
2003
Highly Cited
2003
Ribavirin is a nucleotide analog that can be incorporated by viral polymerases, causing mutations by allowing base mismatches. It… (More)
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Highly Cited
2003
Highly Cited
2003
The RNA-dependent RNA polymerase (NS5B) of hepatitis C virus (HCV) is essential for the replication of viral RNA and thus… (More)
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Highly Cited
1997
Highly Cited
1997
Protein phosphorylation plays a central role in controlling many diverse signal transduction pathways in all cells. Novel protein… (More)
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Highly Cited
1995
Highly Cited
1995
The mechanism of inhibition of HIV-1 reverse transcriptase by three nonnucleoside inhibitors is described. Nevirapine, O-TIBO… (More)
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Highly Cited
1982
Highly Cited
1982
The chicken muscle tissue culture system has been used for visualizing actin gene expression after in situ hybridization. Cell… (More)
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