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Analog

Known as: Analogue, analogs 
A synthetic chemical which structurally or functionally resembles a naturally occurring compound.
National Institutes of Health

Related topics

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16 relations

Broader (1)

Chemicals

Narrower (14)

CoenzymesNucleoside Analogsaminoacid analogbenzimidazole analog
analogs & derivatives

Papers overview

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Highly Cited
1985
Highly Cited
1985
Evidence for a role for cellular alkalinization in the cyclic adenosine 3',5'-monophosphate-mediated initiation of motility in bovine caput spermatozoa.
Bicarbonate ion, the local anesthetics procaine and dibucaine, and the ionophores monensin and nigericin have been shown to… 
Highly Cited
1983
Highly Cited
1983
Myocardial imaging and metabolic studies with [17-123I]iodoheptadecanoic acid in patients with idiopathic congestive cardiomyopathy.
In twenty patients with primary congestive cardiomyopathy (COCM) the patterns of accumulation and washout of the fatty acid… 
Highly Cited
1983
Highly Cited
1983
Phase I and clinical pharmacology studies of intravenous and oral administration of 4-demethoxydaunorubicin in patients with advanced cancer.
4-Demethoxydaunorubicin (4-DMDR), an anthracycline analogue available in i.v. and p.o. form, has shown significant antitumor… 
Highly Cited
1982
Highly Cited
1982
Crystal structure determinations of coenzyme analogue and substrate complexes of liver alcohol dehydrogenase: binding of 1,4,5,6-tetrahydronicotinamide adenine dinucleotide and trans-4-(N,N…
Highly Cited
1981
Highly Cited
1981
Immunohistochemical evidence for a "neurotoxic" action of (D-Pro2, D-Trp7,9)-substance P, an analogue with substance P antagonistic activity.
Highly Cited
1980
Highly Cited
1980
Binding of coenzyme analogues to Lactobacillus casei dihydrofolate reductase: binary and ternary complexes.
The binding, or association, constants of NADP+ NADPH, and a series of structural analogues to dihydrofolate reductase from… 
Highly Cited
1978
Highly Cited
1978
The relationship between enkephalin degradation and opiate receptor occupancy.
Enkephalin, a brain peptide with morphine-like activities, is rapidly inactivated by a membrane-associated aminopeptidase present… 
Highly Cited
1977
Highly Cited
1977
Prostaglandin endoperoxides and thromboxane A2 can induce platelet aggregation in the absence of secretion
PLATELET aggregation and secretion are widely studied not only because they are believed to reflect the major in vivo platelet… 
Highly Cited
1976
Highly Cited
1976
Factors affecting substrate binding in Lactobacillus casei thymidylate synthetase as studied by equilibrium dialysis.
The binding of deoxynucleoside 5'-monophosphates and various folate derivatives to Lactobacillus casei thymidylate synthetase was… 
Highly Cited
1976
Highly Cited
1976
Changes in the secretion of ovarian steroid and pituitary luteinizing hormone in the peri-ovulatory period in the ewe: the effect of progesterone.
The secretion rates of oestradiol, androstenedione and progesterone and the peripheral plasma concentration of LH were measured…