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normeperidine
Known as:
norpethidine
National Institutes of Health
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Related topics
Related topics
5 relations
Broader (2)
Cholinesterase Inhibitors
Meperidine
Normeperidine/Creatinine:MRto:Pt:Urine:Qn
Normeperidine:PrThr:Pt:Urine:Ord:Confirm
analogs & derivatives
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2009
Review
2009
Role of active metabolites in the use of opioids
J. Coller
,
L. Christrup
,
A. Somogyi
European Journal of Clinical Pharmacology
2009
Corpus ID: 9977741
The opioid class of drugs, a large group, is mainly used for the treatment of acute and chronic persistent pain. All are…
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Review
1999
Review
1999
Pharmacokinetics of Opioids in Liver Disease
I. Tegeder
,
J. Lötsch
,
G. Geisslinger
Clinical Pharmacokinetics
1999
Corpus ID: 36147855
The liver is the major site of biotransformation for most opioids. Thus, the disposition of these drugs may be affected in…
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Highly Cited
1997
Highly Cited
1997
Effects of routinely given pethidine during labour on infants' developing breastfeeding behaviour. Effects of dose‐delivery time interval and various concentrations of pethidine/norpethidine in cord…
E. Nissen
,
A. Widström
,
+4 authors
L. Boréus
Acta paediatrica
1997
Corpus ID: 26046290
A standard dose of 100 mg of pethidine was given im to 13 healthy primiparae during labour. The aim of the study was to…
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Review
1996
Review
1996
Pharmacokinetics of Opioids in Renal Dysfunction
G. Davies
,
C. Kingswood
,
M. Street
Clinical Pharmacokinetics
1996
Corpus ID: 38040306
SummaryPatients with renal insufficiency commonly require the administration of an opioid analgesic to provide adequate pain…
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Highly Cited
1993
Highly Cited
1993
Norpethidine toxicity and patient controlled analgesia.
P. Stone
,
P. Macintyre
,
D. A. Jarvis
British Journal of Anaesthesia
1993
Corpus ID: 45607834
Patient-controlled analgesia (PCA) with i.v. opioids is prescribed increasingly. We report three cases of norpethidine toxicity…
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Review
1990
Review
1990
Pro‐ and Anticonvulsant Effects of Anesthetics (Part II)
P. Modica
,
R. Tempelhoff
,
P. White
Anesthesia and Analgesia
1990
Corpus ID: 33479743
Many inhaled anesthetics and intravenous analgesics have been alleged to produce both proconvulsant and anticonvulsant activity…
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Review
1983
Review
1983
Central nervous system excitatory effects of meperidine in cancer patients
R. Kaiko
,
K. Foley
,
+4 authors
M. Reidenberg
Annals of Neurology
1983
Corpus ID: 44353966
The analgesic meperidine has been reported to produce signs of central nervous system excitation in human beings. To determine…
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Highly Cited
1981
Highly Cited
1981
Neonatal depression after obstetrical analgesia with pethidine. the role of the injection‐delivery time interval and of the plasma concentrations of pethidine and norpethidine
P. Belfrage
,
L. Boréus
,
P. Hartvig
,
L. Irestedt
,
N. Raabe
Acta Obstetricia et Gynecologica Scandinavica
1981
Corpus ID: 32207442
Pethidine (100 mg) was administered i.m. to women in labor at different times before delivery. The interval before respiration in…
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Highly Cited
1977
Highly Cited
1977
Accumulation of normeperidine, an active metabolite of meperidine, in patients with renal failure of cancer.
H. Szeto
,
C. Inturrisi
,
R. Houde
,
S. Saal
,
J. Cheigh
,
M. Reidenberg
Annals of Internal Medicine
1977
Corpus ID: 38565898
Concentrations of meperidine and its active metabolite, normeperidine, were measured in plasma of patients receiving the drug for…
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Review
1976
Review
1976
Pharmacologically Active Drug Metabolites: Therapeutic and Toxic Activities, Plasma and Urine Data in Man, Accumulation in Renal Failure
D. Drayer
Clinical Pharmacokinetics
1976
Corpus ID: 8523402
SummaryDrugs that are administered to man may be biotransformed to yield metabolites that are pharmacologically active. The…
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