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normeperidine

Known as: norpethidine 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (2)

Cholinesterase InhibitorsMeperidine
Normeperidine/Creatinine:MRto:Pt:Urine:QnNormeperidine:PrThr:Pt:Urine:Ord:Confirmanalogs & derivatives

Papers overview

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Review
2009
Review
2009
Role of active metabolites in the use of opioids
The opioid class of drugs, a large group, is mainly used for the treatment of acute and chronic persistent pain. All are… 
Review
1999
Review
1999
Pharmacokinetics of Opioids in Liver Disease
The liver is the major site of biotransformation for most opioids. Thus, the disposition of these drugs may be affected in… 
Highly Cited
1997
Highly Cited
1997
Effects of routinely given pethidine during labour on infants' developing breastfeeding behaviour. Effects of dose‐delivery time interval and various concentrations of pethidine/norpethidine in cord…
A standard dose of 100 mg of pethidine was given im to 13 healthy primiparae during labour. The aim of the study was to… 
Review
1996
Review
1996
Pharmacokinetics of Opioids in Renal Dysfunction
SummaryPatients with renal insufficiency commonly require the administration of an opioid analgesic to provide adequate pain… 
Highly Cited
1993
Highly Cited
1993
Norpethidine toxicity and patient controlled analgesia.
Patient-controlled analgesia (PCA) with i.v. opioids is prescribed increasingly. We report three cases of norpethidine toxicity… 
Review
1990
Review
1990
Pro‐ and Anticonvulsant Effects of Anesthetics (Part II)
Many inhaled anesthetics and intravenous analgesics have been alleged to produce both proconvulsant and anticonvulsant activity… 
Review
1983
Review
1983
Central nervous system excitatory effects of meperidine in cancer patients
The analgesic meperidine has been reported to produce signs of central nervous system excitation in human beings. To determine… 
Highly Cited
1981
Highly Cited
1981
Neonatal depression after obstetrical analgesia with pethidine. the role of the injection‐delivery time interval and of the plasma concentrations of pethidine and norpethidine
Pethidine (100 mg) was administered i.m. to women in labor at different times before delivery. The interval before respiration in… 
Highly Cited
1977
Highly Cited
1977
Accumulation of normeperidine, an active metabolite of meperidine, in patients with renal failure of cancer.
Concentrations of meperidine and its active metabolite, normeperidine, were measured in plasma of patients receiving the drug for… 
Review
1976
Review
1976
Pharmacologically Active Drug Metabolites: Therapeutic and Toxic Activities, Plasma and Urine Data in Man, Accumulation in Renal Failure
  • D. Drayer
  • Clinical Pharmacokinetics
  • 1976
  • Corpus ID: 8523402
SummaryDrugs that are administered to man may be biotransformed to yield metabolites that are pharmacologically active. The… 
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