normeperidine

The opioid class of drugs, a large group, is mainly used for the treatment of acute and chronic persistent pain. All are… Expand

The liver is the major site of biotransformation for most opioids. Thus, the disposition of these drugs may be affected in… Expand

A standard dose of 100 mg of pethidine was given im to 13 healthy primiparae during labour. The aim of the study was to… Expand

SummaryPatients with renal insufficiency commonly require the administration of an opioid analgesic to provide adequate pain… Expand

Patient-controlled analgesia (PCA) with i.v. opioids is prescribed increasingly. We report three cases of norpethidine toxicity… Expand

1 Campbell S, Pearce JMF. The prenatal diagnosis of foetal strictural anomalies by ultrasound. Clin Obstet Gynaecol 1983;10:475… Expand

Pethidine (100 mg) was administered i.m. to women in labor at different times before delivery. The interval before respiration in… Expand

In an attempt to improve postoperative pain management an intravenous infusion of pethidine was designed to provide stable… Expand

Concentrations of meperidine and its active metabolite, normeperidine, were measured in plasma of patients receiving the drug for… Expand

SummaryDrugs that are administered to man may be biotransformed to yield metabolites that are pharmacologically active. The… Expand