normeperidine

The opioid class of drugs, a large group, is mainly used for the treatment of acute and chronic persistent pain. All are… (More)

The liver is the major site of biotransformation for most opioids. Thus, the disposition of these drugs may be affected in… (More)

A standard dose of 100 mg of pethidine was given im to 13 healthy primiparae during labour. The aim of the study was to… (More)

Seizures are common in acute exacerbations of hepatic porphyria, even though the etiology is not identified in most cases. We… (More)

Perioperative seizures have numerous potential etiologies. In general, when seizures occur during surgery, their onset often… (More)

The presystemic metabolism of meperidine to normeperidine was examined in four healthy men before, during, and 3 wk after… (More)

Plasma concentrations and urinary excretion of meperidine and its metabolite normeperidine were determined after intravenous and… (More)

Pethidine (100 mg) was administered i.m. to women in labor at different times before delivery. The interval before respiration in… (More)

In an attempt to improve postoperative pain management an intravenous infusion of pethidine was designed to provide stable… (More)

Naloxone antagonized convulsions produced by tail vein infusions of d-propoxyphene, heroin, meperidine, normeperidine and… (More)