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Meperidine

Known as: Pethidinum, Petidina, Petydyna 
A synthetic piperidine ester with opioid analgesic activity. Meperidine mimics the actions of endogenous neuropeptides via opioid receptors, thereby… 
National Institutes of Health

Related topics

Related topics

40 relations
1 ML Meperidine Hydrochloride 100 MG/ML Injection [Demerol]In BloodMeperidine:MCnc:Pt:Gast fld:QnMeperidine:MRat:24H:Urine:Qn

Narrower (15)

4-propionyloxy-4-phenyl-N-methylpiperidineDemerolDolantinDolargan

Broader (8)

Adjuvants, AnesthesiaAminesAnalgesicsAntispasmodics

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1993
Highly Cited
1993
Synthetic and natural opiates interact with P-glycoprotein in multidrug-resistant cells.
Highly Cited
1989
Highly Cited
1989
Comparison of ketamine and pethidine in experimental and postoperative pain
Highly Cited
1987
Highly Cited
1987
Pharmacokinetics of Epidural Morphine and Meperidine in Humans
Five groups of surgical patients, each comprising six individuals, received epidural doses of morphine or meperidine, and the… 
Highly Cited
1984
Highly Cited
1984
Oxidation of the neurotoxic amine 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) by monoamine oxidases A and B and suicide inactivation of the enzymes by MPTP.
Highly Cited
1982
Highly Cited
1982
Drug metabolism by rat and human hepatic microsomes in response to interaction with H2-receptor antagonists
Highly Cited
1980
Highly Cited
1980
Relationship Between Blood Meperidine Concentrations and Analgesic Response: A Preliminary Report
Variability in analgesic responses to intramuscularly administered meperidine has been related to variable and unpredictable… 
Highly Cited
1979
Highly Cited
1979
Enhanced bioavailability and decreased clearance of analgesics in patients with cirrhosis.
Highly Cited
1979
Highly Cited
1979
A Pharmacokinetic Approach to Postoperative Pain: Continuous Infusion of Pethidine
In an attempt to improve postoperative pain management an intravenous infusion of pethidine was designed to provide stable… 
Highly Cited
1975
Highly Cited
1975
The effects of premedication drugs on the lower oesophageal high pressure zone and reflux status of rhesus monkeys and man.
Thirty-five human volunteers and eight Rhesus monkeys were studied with standard gastrooesophageal manometric techniqes and their… 
Highly Cited
1955
Highly Cited
1955
Enzymatic dealkylation of aminopyrine (pyramidon) and other alkylamines.
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