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noribogaine

Known as: 12-OH-ibogamine, 12-hydroxy-ibogamine, 12-hydroxyibogamine 
National Institutes of Health

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Broader (1)

Ibogaine
analogs & derivatives

Papers overview

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2013
2013
Effect of Iboga Alkaloids on µ-Opioid Receptor-Coupled G Protein Activation
Objective The iboga alkaloids are a class of small molecules defined structurally on the basis of a common ibogamine skeleton… 
2006
2006
Ibogaine and Noribogaine: Comparing Parent Compound to Metabolite
Ibogaine is one of the psychoactive alkaloids found in the West African shrub Tabernanthe iboga. Since the 1980s, a series of US… 
2005
2005
Quantitation of ibogaine and 12-hydroxyibogamine in human plasma by liquid chromatography with fluorimetric detection.
Highly Cited
2000
Highly Cited
2000
Development of Novel Medications for Drug Addiction: The Legacy of an African Shrub
Abstract: Ibogaine, one of several alkaloids found in the root bark of the African shrub Tabernanthe iboga, has been claimed to… 
1998
1998
Noribogaine stimulates naloxone-sensitive [35S]GTPgammaS binding.
Noribogaine is formed in vivo by the O-demethylation of the indole alkaloid ibogaine. We report here that noribogaine acts as a… 
Review
1998
Review
1998
Medication development of ibogaine as a pharmacotherapy for drug dependence.
The potential for deriving new psychotherapeutic medications from natural sources has led to renewal interest in rain forest… 
1998
1998
Modified ibogaine fragments: synthesis and preliminary pharmacological characterization of 3-ethyl-5-phenyl-1,2,3,4,5, 6-hexahydroazepino[4,5-b]benzothiophenes.
Five phenyl-substituted derivatives and analogues of 1,2,3,4,5, 6-hexahydroazepino[4,5-b]indole, 5, a major fragment of ibogaine… 
1997
1997
Time-dependent interactions between iboga agents and cocaine.
1997
1997
Effects of ibogaine and noribogaine on the antinociceptive action of mu-, delta- and kappa-opioid receptor agonists in mice.
Ibogaine, an alkaloid isolated from the bark of the African shrub, Tabernanthe iboga, has been claimed to decrease the self… 
Highly Cited
1995
Highly Cited
1995
Radioligand-binding study of noribogaine, a likely metabolite of ibogaine
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