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non-ribosomal peptide synthase
Known as:
NRPS enzyme
, NrpG synthase
, nonribosomal peptide synthase
National Institutes of Health
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peptide synthase
Papers overview
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2018
2018
Fungal Isocyanide Synthases and Xanthocillin Biosynthesis in Aspergillus fumigatus
Fang Yun Lim
,
Tae Hyung Won
,
+5 authors
N. Keller
mBio
2018
Corpus ID: 44135965
ABSTRACT Microbial secondary metabolites, including isocyanide moieties, have been extensively mined for their repertoire of…
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2016
2016
Engineering Fungal Nonribosomal Peptide Synthetase-like Enzymes by Heterologous Expression and Domain Swapping.
Johannes W A van Dijk
,
Chun-Jun Guo
,
Clay C. C. Wang
Organic Letters
2016
Corpus ID: 45671472
A facile genetic methodology in the filamentous fungus Aspergillus nidulans allowed the exchange of various domains in…
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Highly Cited
2015
Highly Cited
2015
Comparative genomics and metabolic profiling of the genus Lysobacter
I. de Bruijn
,
Xu Cheng
,
+7 authors
J. Raaijmakers
BMC Genomics
2015
Corpus ID: 5942623
BackgroundLysobacter species are Gram-negative bacteria widely distributed in soil, plant and freshwater habitats. Lysobacter…
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2014
2014
Aryl-aldehyde formation in fungal polyketides: discovery and characterization of a distinct biosynthetic mechanism.
M. Wang
,
Mirko Beissner
,
Huimin Zhao
Chemistry and Biology
2014
Corpus ID: 5109748
Highly Cited
2014
Highly Cited
2014
Nonribosomal Peptide Synthase Gene Clusters for Lipopeptide Biosynthesis in Bacillus subtilis 916 and Their Phenotypic Functions
C. Luo
,
Xuehui Liu
,
Huafei Zhou
,
Xiaoyu Wang
,
Zhiyi Chen
Applied and Environmental Microbiology
2014
Corpus ID: 11580336
ABSTRACT Bacillus cyclic lipopeptides (LPs) have been well studied for their phytopathogen-antagonistic activities. Recently…
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2013
2013
Complexity generation in fungal peptidyl alkaloid biosynthesis: a two-enzyme pathway to the hexacyclic MDR export pump inhibitor ardeemin.
S. Haynes
,
Xue Gao
,
Yi Tang
,
C. Walsh
ACS Chemical Biology
2013
Corpus ID: 42857634
Ardeemins are hexacyclic peptidyl alkaloids isolated from Aspergillus fischeri as agents that block efflux of anticancer drugs by…
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Highly Cited
2012
Highly Cited
2012
Production of the Antimicrobial Secondary Metabolite Indigoidine Contributes to Competitive Surface Colonization by the Marine Roseobacter Phaeobacter sp. Strain Y4I
W. N. Cude
,
Jason P Mooney
,
+5 authors
A. Buchan
Applied and Environmental Microbiology
2012
Corpus ID: 206717704
ABSTRACT Members of the Roseobacter lineage of marine bacteria are prolific surface colonizers in marine coastal environments…
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2012
2012
Antifungal spectrum, in vivo efficacy, and structure-activity relationship of ilicicolin h.
Sheo B. Singh
,
Weiguo Liu
,
+14 authors
J. Onishi
ACS Medicinal Chemistry Letters
2012
Corpus ID: 847511
Ilicicolin H is a polyketide-nonribosomal peptide synthase (NRPS)-natural product isolated from Gliocadium roseum, which exhibits…
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Highly Cited
2005
Highly Cited
2005
Functional Analysis of All Nonribosomal Peptide Synthetases in Cochliobolus heterostrophus Reveals a Factor, NPS6, Involved in Virulence and Resistance to Oxidative Stress
Bee-Na Lee
,
S. Kroken
,
D. Y. Chou
,
B. Robbertse
,
O. Yoder
,
B. Turgeon
Eukaryotic Cell
2005
Corpus ID: 15040243
ABSTRACT Nonribosomal peptides, made by nonribosomal peptide synthetases, have diverse biological activities, including roles as…
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2003
2003
Naturally mosaic operons for secondary metabolite biosynthesis: variability and putative horizontal transfer of discrete catalytic domains of the epothilone polyketide synthase locus
J. V. Lopez
Zeitschrift für Induktive Abstammungs- und…
2003
Corpus ID: 21201734
A putative instance of horizontal gene transfer (HGT) involving adjacent, discrete β-ketoacyl synthase (KS), acyl carrier protein…
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