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non-ribosomal peptide synthase

Known as: NRPS enzyme, NrpG synthase, nonribosomal peptide synthase 
 
National Institutes of Health

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peptide synthase

Papers overview

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2016
2016
Engineering Fungal Nonribosomal Peptide Synthetase-like Enzymes by Heterologous Expression and Domain Swapping.
A facile genetic methodology in the filamentous fungus Aspergillus nidulans allowed the exchange of various domains in… Expand
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Highly Cited
2015
Highly Cited
2015
Comparative genomics and metabolic profiling of the genus Lysobacter
BackgroundLysobacter species are Gram-negative bacteria widely distributed in soil, plant and freshwater habitats. Lysobacter… Expand
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2015
2015
Antimicrobial activity of Alcaligenes sp. HPC 1271 against multidrug resistant bacteria
Alcaligenes sp. HPC 1271 demonstrated antibacterial activity against multidrug resistant bacteria, Enterobacter sp., resistant to… Expand
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2014
2014
Aryl-aldehyde formation in fungal polyketides: discovery and characterization of a distinct biosynthetic mechanism.
Aryl-aldehydes are a common feature in fungal polyketides, which are considered to be exclusively generated by the R domain of… Expand
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2014
2014
Nonribosomal Peptide Synthase Gene Clusters for Lipopeptide Biosynthesis in Bacillus subtilis 916 and Their Phenotypic Functions
ABSTRACT Bacillus cyclic lipopeptides (LPs) have been well studied for their phytopathogen-antagonistic activities. Recently… Expand
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2013
2013
Complexity generation in fungal peptidyl alkaloid biosynthesis: a two-enzyme pathway to the hexacyclic MDR export pump inhibitor ardeemin.
Ardeemins are hexacyclic peptidyl alkaloids isolated from Aspergillus fischeri as agents that block efflux of anticancer drugs by… Expand
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Highly Cited
2012
Highly Cited
2012
Production of the Antimicrobial Secondary Metabolite Indigoidine Contributes to Competitive Surface Colonization by the Marine Roseobacter Phaeobacter sp. Strain Y4I
ABSTRACT Members of the Roseobacter lineage of marine bacteria are prolific surface colonizers in marine coastal environments… Expand
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2012
2012
Antifungal spectrum, in vivo efficacy, and structure-activity relationship of ilicicolin h.
Ilicicolin H is a polyketide-nonribosomal peptide synthase (NRPS)-natural product isolated from Gliocadium roseum, which exhibits… Expand
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Highly Cited
2005
Highly Cited
2005
Functional Analysis of All Nonribosomal Peptide Synthetases in Cochliobolus heterostrophus Reveals a Factor, NPS6, Involved in Virulence and Resistance to Oxidative Stress
ABSTRACT Nonribosomal peptides, made by nonribosomal peptide synthetases, have diverse biological activities, including roles as… Expand
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2003
2003
Naturally mosaic operons for secondary metabolite biosynthesis: variability and putative horizontal transfer of discrete catalytic domains of the epothilone polyketide synthase locus
  • J. V. Lopez
  • Molecular Genetics and Genomics
  • 2003
    • Corpus ID: 21201734
A putative instance of horizontal gene transfer (HGT) involving adjacent, discrete β-ketoacyl synthase (KS), acyl carrier protein… Expand
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