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nicaraven
Known as:
1,2-bis(nicotinamido)propane
, N,N'-propylenebis(nicotinamide)
National Institutes of Health
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Related topics
Related topics
3 relations
Broader (2)
Antioxidants
Niacinamide
analogs & derivatives
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2003
Review
2003
Nicaraven Chugai.
R. Leker
Current opinion in investigational drugs
2003
Corpus ID: 34303282
Chugai (the Japanese subsidiary of Roche) is developing nicaraven (Antevas), a water-soluble antioxidant, for the potential…
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2000
2000
Effects of nicaraven on nitric oxide-related pathways and in shock and inflammation.
B. Zingarelli
,
G. Scott
,
P. Hake
,
A. Salzman
,
C. Szabó
Shock
2000
Corpus ID: 39880771
Expression of the inducible isoform of nitric oxide (NO) synthase, and the formation of peroxynitrite from NO and superoxide are…
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2000
2000
Quantitative analysis of the kinetic constant of the reaction of N,N'-propylenedinicotinamide with the hydroxyl radical using dimethyl sulfoxide and deduction of its structure in chloroform.
T. Akimoto
Chemical and pharmaceutical bulletin
2000
Corpus ID: 35809373
N,N'-Propylenedinicotinamide (Nicaraven) is presently being developed for the treatment of cerebral stroke including subarachnoid…
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Review
2000
Review
2000
Nicaraven for the treatment of cerebral vasospasm in subarachnoid haemorrhage
K. Jain
Expert Opinion on Investigational Drugs
2000
Corpus ID: 31643914
Cerebral vasospasm is a complication of subarachnoid haemorrhage and can cause cerebral ischaemia. Antivasospastic agents are…
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1999
1999
A novel free radical scavenger, nicaraven, inhibits human platelet aggregation in vitro.
T. Komiya
,
K. Higurashi
,
K. Iizuka
,
Y. Mizuno
Clinical neuropharmacology
1999
Corpus ID: 46687157
The present study was undertaken to investigate whether or not radical scavengers can inhibit platelet aggregation in humans…
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1998
1998
Cellular expression of inducible nitric oxide synthase following rat cortical incision and its suppression by hydroxyl radical scavenger, 1,2-bis(nicotinamido)propane
K. Yamanaka
,
E. Kumura
,
+4 authors
T. Hayakawa
Neurosciences research
1998
Corpus ID: 25348561
1998
1998
Protective effect of nicaraven against prolonged cold kidney preservation and reperfusion injury.
Y. Masaki
,
K. Kumano
,
+4 authors
M. Okubo
Transplantation Proceedings
1998
Corpus ID: 26327095
1997
1997
Hydroxyl radical scavenging effect of nicaraven in myocardial and coronary endothelial preservation and reperfusion injury.
M. S. Alam
,
K. Ku
,
+6 authors
K. Tamura
Cardiovascular Research
1997
Corpus ID: 6511264
1996
1996
The role of a hydroxyl radical scavenger (nicaraven) in recovery of cardiac function following preservation and reperfusion.
K. Ku
,
S. Kin
,
+5 authors
K. Nakayama
Transplantation
1996
Corpus ID: 24095542
We investigated the efficacy in reducing myocardial preservation and reperfusion (P/R) injury of direct hydroxyl radical…
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1993
1993
[Experimental studies on Nicaraven as radioprotector--free radical scavenging effect and the inhibition of the cellular injury].
Y. Mori
,
H. Takashima
,
+4 authors
M. Tanabe
Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta…
1993
Corpus ID: 25243146
In the present study, firstly the antioxidant effect of Nicaraven was observed by examining the direct free radical scavenging…
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