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nelarabine

Known as: 2-Amino-6-methoxypurine arabinoside, 2-amino-9-beta-D-arabinofuranosyl-6-methoxy-9H-purine, 2-Amino, 6-Methoxypurine Arabinoside 
An arabinonucleoside antimetabolite with antineoplastic activity. Nelarabine is demethoxylated by adenosine deaminase to become biologically active 9… 
National Institutes of Health

Related topics

Related topics

7 relations

Broader (1)

Arabinonucleosides

Narrower (3)

ArranonGW-506U78GW506U78
DNADNA Synthesis InhibitionNCIt Antineoplastic Agent Terminology

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
A study to evaluate immunological response to PD-1 inhibition in squamous cell carcinoma of the head and neck (SCCHN) using novel PET imaging with [18F]F-AraG.
6050Background: Immune checkpoint blockade has demonstrated remarkable responses in a subset of patients with head and neck… 
2013
2013
Optimized cobalt nanowires for domain wall manipulation imaged by in situ Lorentz microscopy
Direct observation of domain wall (DW) nucleation and propagation in focused electron beam induced deposited Co nanowires as a… 
2012
2012
Association of interactions among the IRF6 gene, the 8q24 region, and maternal folic acid intake with non‐syndromic cleft lip/palate in Mexican Mestizos
Association of Interactions Among the IRF6 Gene, the 8q24 Region, and Maternal Folic Acid Intake With Non-Syndromic Cleft Lip… 
2009
2009
Successful induction therapy with decitabine in refractory childhood acute lymphoblastic leukemia
Successful induction therapy with decitabine in refractory childhood acute lymphoblastic leukemia 
Review
2007
Review
2007
Three new drugs for acute lymphoblastic leukemia: nelarabine, clofarabine, and forodesine.
The search for more effective and safer anti-leukemia therapies has led to the identification of several new agents that show… 
2007
2007
Role of nelarabine in the treatment of T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma
T-cell malignancies have distinct biochemical, immunologic, and clinical features which set them apart from non-T-cell… 
2003
2003
Effects of 9-beta-D-arabinofuranosylguanine on mitochondria in CEM T-lymphoblast leukemia cells.
2002
2002
Identification of residues involved in the substrate specificity of human and murine dCK.
1991
1991
PHARMACOLOGIC PURGING OF MALIGNANT T CELLS FROM HUMAN BONE MARROW USING 9‐β‐D‐ARABINOFURANOSYLGUANINE
Arabinosylguanine (araG) is a nucleoside analog that is rapidly converted by cells of the T lymphoid lineage to its corresponding… 
1987
1987
High-affinity L-arabinose transport operon. Gene product expression and mRNAs.
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