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nelarabine

Known as: 2-Amino-6-methoxypurine arabinoside, 2-amino-9-beta-D-arabinofuranosyl-6-methoxy-9H-purine, 2-Amino, 6-Methoxypurine Arabinoside 
An arabinonucleoside antimetabolite with antineoplastic activity. Nelarabine is demethoxylated by adenosine deaminase to become biologically active 9… Expand
National Institutes of Health

Papers overview

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Highly Cited
2017
Highly Cited
2017
Carbonate clumped isotope thermometry is based on the temperature-dependent formation of ^(13)C^(18)O^(16)O_2^(2-) ion groups… Expand
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2015
2015
BACKGROUND Nelarabine has shown impressive single agent clinical activity in T-cell acute lymphoblastic leukemia (T-ALL), but has… Expand
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Highly Cited
2013
Highly Cited
2013
The potential of stem cell (SC) therapies for eye diseases is well-recognized. However, the results remain only encouraging as… Expand
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Highly Cited
2012
Highly Cited
2012
Abstract. Predicting consequences of ocean deoxygenation and ocean acidification for nearshore marine ecosystems requires… Expand
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Highly Cited
2012
Highly Cited
2012
PURPOSE Children's Oncology Group study AALL00P2 was designed to assess the feasibility and safety of adding nelarabine to a BFM… Expand
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Highly Cited
2011
Highly Cited
2011
Nelarabine, a purine analog with T-cell specific action, has been approved for relapsed/refractory T-cell acute lymphoblastic… Expand
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Highly Cited
2007
Highly Cited
2007
Nelarabine (506U78) is a soluble pro-drug of 9-beta-D-arabinofuranosylguanine (ara-G), a deoxyguanosine derivative. We treated 26… Expand
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Highly Cited
2007
Highly Cited
2007
The impact of 2′-deoxy-2′-fluoroarabinonucleotide residues (2′F-araN) on different G-quadruplexes derived from a thrombin-binding… Expand
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Highly Cited
2005
Highly Cited
2005
PURPOSE Nelarabine (compound 506U78), a water soluble prodrug of 9-b-d-arabinofuranosylguanine, is converted to ara-GTP in T… Expand
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Highly Cited
2004
Highly Cited
2004
An experiment was carried out using 7 month old male calves from four different breeds: 10 Spanish Holstein (dairy), 10 Old Brown… Expand
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