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2'-Deoxy-2'-fluoro-arabinonucleic acid (FANA) and arabinonucleic acid (ANA) paired to RNA are substrates of RNase H. The… Expand Recently, hybrids of RNA and D-arabinonucleic acids (ANA) as well as the 2'-deoxy-2'-fluoro-D-arabinonucleic acid analog (2'F-ANA… Expand Cytosine arabinonucleoside (AraC) is a pyrimidine antimetabolite that kills proliferating cells by inhibiting DNA synthesis and… Expand An approach involving retroviral-mediated gene therapy for the treatment of neoplastic disease is described. This therapeutic… Expand We report here a five-step purification procedure that led to the isolation from fetal calf bone marrow extract of a tetrapeptide… Expand The synthesis of 5-(2-fluoroethyl)-2'-deoxyuridine (FEDU, 4b), its 2'-fluoro analogue 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl… Expand In cultured bovine chromaffin cells, changes in the dynamic state of enkephalin stores elicited experimentally were studied by… Expand Xanthine oxidase [EC 22.214.171.124] was purified 2000-fold from human liver. The last step of the procedure involved affinity… Expand Purine analogues are potentially useful agents for selective chemotherapy of lymphoproliferative diseases. We compared the toxic… Expand A new method for determining nucleotide sequences in DNA is described. It is similar to the "plus and minus" method [Sanger, F… Expand