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negative regulation of isoleucine-tRNA ligase activity

Known as: down regulation of isoleucine-tRNA synthetase activity, down-regulation of isoleucyl-transfer RNA synthetase activity, negative regulation of isoleucyl-transfer RNA synthetase activity 
Any process that stops, prevents or reduces the frequency, rate or extent of isoleucine-tRNA ligase activity. [GO_REF:0000059, GOC:TermGenie, PMID… 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (1)

biological control

Narrower (1)

inhibition of L-isoleucine:tRNAIle ligase (AMP-forming)
isoleucine-tRNA ligase activity

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Life without tRNAIle-lysidine synthetase: translation of the isoleucine codon AUA in Bacillus subtilis lacking the canonical tRNA2Ile
Translation of the isoleucine codon AUA in most prokaryotes requires a modified C (lysidine or agmatidine) at the wobble position… 
2009
2009
The selenocysteine tRNA STAF-binding region is essential for adequate selenocysteine tRNA status, selenoprotein expression and early age survival of mice.
STAF [Sec (selenocysteine) tRNA gene transcription activating factor] is a transcription activating factor for a number of RNA… 
2002
2002
Chiral mutagenesis of insulin's hidden receptor-binding surface: structure of an allo-isoleucine(A2) analogue.
The hydrophobic core of vertebrate insulins contains an invariant isoleucine residue at position A2. Lack of variation may… 
2000
2000
Memory of chirality in diastereoselective alpha-alkylation of isoleucine and allo-isoleucine derivatives.
[reaction: see text] alpha-Methylation of 3 gave 5 as a major product whereas 4 gave 6 predominantly, although both 3 and 4 have… 
2000
2000
Structural relationships in crystals accommodating different stereoisomers of 2-amino-3-methylpentanoic acid.
A reinvestigation of the crystal structure of the 1:1 mixture of the two racemates DL-isoleucine and DL-allo-isoleucine, with a… 
1988
1988
Neonatal hyperphenylalaninaemia presumably caused by a new variant of biopterin synthetase defieiency
Systematic investigation of hyperphenylalaninaemic infants for tetrahydrobiopterin deficiency has recently led to the description… 
1981
1981
Factors modulating transcription and translation in vitro of ribosomal protein S20 and isoleucyl-tRNA synthetase from Escherichia coli.
The DNA-dependent protein-synthesizing system developed by Zubay [Zubay, G. (1973) Annu. Rev. Genet. 7, 267--287] was optimized… 
1979
1979
Energy cost of proofreading to increase fidelity of transfer ribonucleic acid aminoacylation.
The paradox of relatively error free function in biological systems composed of relatively error prone components has recently… 
1975
1975
The mechanism of aminoacylation of transfer ribonucleic acid. Reactivity of enzyme-bound isoleucyl adenylate.
1968
1968
Species specificity in the biosynthesis of branched paraffins in leaves.
Isobutyrate-1-(14)C and l-isoleucine-U-(14)C fed through the petiole labeled the surface lipids of broccoli leaves, but the… 
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