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naxagolide

Known as: 4-propyl-9-hydroxy-1,2,3,4a,5,6-hexahydronaphthoxazine, 4-propyl-9-hydroxynaphthoxazine, (+)-4-propyl-9-hydroxynaphthoxazine 
National Institutes of Health

Papers overview

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2019
2019
Background: Glioblastoma multiforme (GBM) is a common and lethal cancer of the central nervous system. This cancer is difficult… Expand
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2010
2010
Clinical trials have demonstrated positive proof of efficacy of dual metabotropic glutamate receptor 2/3 (mGluR2/3) agonists in… Expand
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Highly Cited
2006
Highly Cited
2006
[11C]‐(+)‐PHNO (4‐propyl‐9‐hydroxynaphthoxazine) is a new agonist radioligand that provides a unique opportunity to measure the… Expand
Highly Cited
1996
Highly Cited
1996
  • M. Kleven, W. Koek
  • The Journal of pharmacology and experimental…
  • 1996
  • Corpus ID: 13451639
Spontaneous eye blink rate was assessed in cynomolgus monkeys treated intramuscularly with the high-efficacy dopamine (DA… Expand
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1994
1994
1 Electrophysiological recordings were made from presumed dopaminergic neurones in the substantia nigra pars compacta and ventral… Expand
1991
1991
The enantiomers of a series of dopamine (DA) agonists, monohydroxy-2-aminotetralin derivatives, were investigated using brain… Expand
1990
1990
4‐‐Propyl‐9‐hydroxynaphthoxazine, or MK‐458 (HPMC), a selective, nonergot D2 agonist administered orally twice a day in sustained… Expand
1990
1990
Metabolism of dopazinol (DZ) by liver microsomes from control and phenobarbital- and 3-methylcholanthrene-treated rats has been… Expand
1985
1985
The intrinsic activity of the potent dopamine (DA) agonist 4-propyl-9-hydroxynaphthoxazine [(+)-PHNO] was examined in receptor… Expand
Highly Cited
1984
Highly Cited
1984
The (+)-enantiomer of 1,2,3,4a,5,6-hexahydro-9-hydroxy-4-n-propyl-4H-naphth[1,2-b][ 1,4]-oxazine [(+)-PHNO] is demonstrated to be… Expand