Oxazines

Known as: Oxazines [Chemical/Ingredient], oxazine 
Six-membered heterocycles containing an oxygen and a nitrogen.
National Institutes of Health

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1,3-diaza-2-oxophenoxazine1-methyl-7-nitroisatoic anhydride2-hydroxyisophenoxazin-3-one2-morpholino-chromen-oxazine-dione
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In Bloodagonistsantagonists & inhibitorschemical synthesis

Papers overview

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2014
2014
Oxazine derivatives of γ- and δ-tocotrienol display enhanced anticancer activity in vivo.
BACKGROUND Oxazine derivatives of tocotrienols display enhanced anticancer activity. Studies were conducted to further… (More)
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Highly Cited
2009
Highly Cited
2009
Controlling the fluorescence of ordinary oxazine dyes for single-molecule switching and superresolution microscopy.
Fluorescent molecular switches have widespread potential for use as sensors, material applications in electro-optical data… (More)
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Highly Cited
2008
Highly Cited
2008
Powerful bactericidal and sterilizing activity of a regimen containing PA-824, moxifloxacin, and pyrazinamide in a murine model of tuberculosis.
PA-824 is a nitroimidazo-oxazine in clinical testing for the treatment of tuberculosis. We report that the novel combination of… (More)
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2008
2008
Synthesis and antitubercular activity of 7-(R)- and 7-(S)-methyl-2-nitro-6-(S)-(4-(trifluoromethoxy)benzyloxy)-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazines, analogues of PA-824.
Nitroimidazoles such as PA-824 and OPC-67683 are currently in clinical development as members of a promising new class of… (More)
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Highly Cited
2006
Highly Cited
2006
Identification of a nitroimidazo-oxazine-specific protein involved in PA-824 resistance in Mycobacterium tuberculosis.
PA-824 is a promising new compound for the treatment of tuberculosis that is currently undergoing human trials. Like its… (More)
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2006
2006
Chromogenic oxazines for cyanide detection.
[reaction: see text] We have designed two heterocyclic compounds for the colorimetric detection of cyanide. The skeleton of both… (More)
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Highly Cited
2005
Highly Cited
2005
In vivo detection of amyloid-β deposits by near-infrared imaging using an oxazine-derivative probe
As Alzheimer's disease pathogenesis is associated with the formation of insoluble aggregates of amyloid β-peptide, approaches… (More)
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Highly Cited
1999
Highly Cited
1999
A sensitive, viable-colony staining method using Nile red for direct screening of bacteria that accumulate polyhydroxyalkanoic acids and other lipid storage compounds
The oxazine dye Nile blue A and its fluorescent oxazone form, Nile red, were used to develop a simple and highly sensitive… (More)
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1995
1995
Antimalarial dyes revisited: xanthenes, azines, oxazines, and thiazines.
In 1891 Guttmann and Ehrlich (P. Guttmann and P. Ehrlich, Berlin Klin. Wochenschr. 28:953-956, 1891) were the first to report the… (More)
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Highly Cited
1981
Highly Cited
1981
Flow cytometric estimation of DNA and RNA content in intact cells stained with Hoechst 33342 and pyronin Y.
The addition of RNA content estimation to flow cytometric measurement of DNA content provides valuable information concerning… (More)
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