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Heterogeneity of tumor cells.
Investigations of cell clones isolated in vitro, or selected in vivo, have shown that tumor cell populations are heterogenous. The isolated cell clones or cell subpopulations originating from aExpand
Comparison of nitrogen‐mustard‐sensitive and ‐resistant yoshida sarcomas
The Yoshida sarcoma and a line derived from it showing acquired resistance to alkylating agents have been compared from a number of aspects: chromosome number, growth rate, nucleic acid, protein andExpand
Some properties of coupled hepatoma mitochondria exhibiting uncoupler-insensitive ATPase activity.
Summary Coupled mitochondria of Zajdela hepatoma exhibited ATPase activity which was not stimulated by uncouplers. In spite of this fact the properties of respiration, energy-dependent Ca2+ uptakeExpand
Drug resistance induction and cross-resistance studies with Pt-complexes.
In vitro drug resistance was induced against cis-diamminedichloroplatinum(II) (cis-DDP), 1,2-diaminocyclohexaneplatinum-(II)citrate (PEX) and 1,2-diaminocyclohexaneplatinum(II)glucarate (PTU) inExpand