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nanaomycin A

Known as: (1S,3R)-3,4,5,10-Tetrahydro-9-hydroxy-1-methyl-5,10-dioxo-1H-naphtho[2,3-c]pyran-3-acetic Acid, NANAFROCIN 
A quinone antibiotic isolated from Streptomyces rosa var. notoensis with activity against gram-positive bacteria, mycoplasmas and fungi. Within an… 
National Institutes of Health

Related topics

Related topics

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Broader (1)

Naphthoquinones

Papers overview

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2017
2017
Four New Nanaomycins Produced by Streptomyces hebeiensis Derived from Lichen
Four new nanaomycins (1 – 4), together with two known compounds, nanaomycin αA (5) and nanaomycin βA (6) were isolated from a… 
1999
1999
Heme-dependent radical generation: possible involvement in antimalarial action of non-peroxide microbial metabolites, nanaomycin A and radicicol.
Antimalarial screening was performed for microbial metabolites that simulate artemisinin in their mode of action, a potent… 
1990
1990
Site of regulation of nanaomycin biosynthesis by inorganic phosphate.
The site of regulation of nanaomycin biosynthesis by inorganic phosphate was studied with washed cells previously grown in a… 
Highly Cited
1987
Highly Cited
1987
Synthesis of deoxyfrenolicin and nanaomycin A
Deoxyfrenolicin and nanaomycin A have been synthesized. Key steps in the synthesis include a phthalide annulation reaction to… 
1982
1982
Biosynthesis of nanaomycin. III. Nanaomycin A formation from nanaomycin D by nanaomycin D reductase via a hydroquinone.
Nanaomycin D reductase which is involved in the biosynthesis of the antifungal antibiotic nanaomycin catalyzes the formation of… 
1981
1981
Biosynthesis of nanaomycin: syntheses of nanaomycin E from nanaomycin A and of nanaomycin B from nanaomycin E in a cell-free system.
The enzyme reactions from NNM-A to NNM-E and from NNM-E to NNM-B were established in a cell-free system containing an extract… 
1981
1981
Biosynthesis of nanaomycin. II. Purification and properties of nanaomycin D reductase involved in the formation of nanaomycin A from nanaomycin D1.
Nanaomycin D reductase, catalyzing the conversion of nanaomycin D to nanaomycin A, which is the first step in the biosynthetic… 
1980
1980
Bioconversion and biosynthesis of nanaomycins using cerulenin, a specific inhibitor of fatty acid and polyketide biosyntheses.
The biosynthetic relationship of the nanaomycins produced by Streptomyces rosa var. notoensis OS-3966 was studied by means of a… 
1980
1980
[The therapeutic effect of nanaomycin A against experimental Trichophyton mentagrophytes infection in guinea pigs (author's transl)].
Acute toxicity of nanaomycin A was tested in mice and rats. It was found that the antibiotic was well absorbed topically so that… 
1979
1979
Structure of nanaomycin E, a new nanaomycin.
A new component, nanaomycin E, has been isolated from the culture broth of Streptomyces rosa var, notoensis, which had been found… 
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